PMID: 18714419Aug 21, 2008Paper

Neonatal thyrotropinemia (TSH) as an indicator of iodine nutritional level in Castellon and Valencia, Spain (2004-2006)

Revista española de salud pública
Carmen Barona-VilarAna Fullana-Montoro

Abstract

In the congenital hypothyroidism screening in populations with sufficient iodine intake, in the percentage of newborns with TSH values 5 mU/l must be less than 3%. This study is aimed at ascertaining the prevalence of iodine deficiency among the mothers and newborns in Castellon and Valencia and, secondly, to evaluate the bearing which the day on which the sample is taken and the use of iodized antiseptics may have. The TSH value was studied in 91,853 newborns within the 2004-2006 period in Castellon and Valencia. The mean TSH values were compared considering the conditions defined by the WHO for analyzing the indicator: sampling at two days following birth and no use of antiseptics. The percentages of samples having TSH5 > mU/l.were calculated and compared. Among the samples having fulfilled the requirements for the analysis of the indicator, the prevalence of newborns having TSH5 > mlU/ showed a decrease from 2004 (2.2% CI95%:1.8%-2.6%), 2005 (2%; CI95%:1.6%-2.3%) and 2006 (1.7%; CI95%: 1.4%-2%). The mean TSH in samples of under 2 days was significantly higher (2.19 mlU/L; Q1-Q3: 1.35-3.40 as compared to 1.36 mlU/L; Q1-Q3: 0.78-2.21) (p<0,001). Considering the samples taken 2 days after birth, the use of antiseptics determine...Continue Reading

Citations

Aug 27, 2009·Journal of Exposure Science & Environmental Epidemiology·Maria-Jose Lopez-EspinosaFerran Ballester
Jul 19, 2019·PloS One·Ernesto Cortés-CastellMaría Mercedes Rizo-Baeza
Mar 10, 2011·American Journal of Epidemiology·Mario MurciaFerran Ballester

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