PMID: 6948125Jan 1, 1982

Neoplasms following childhood radium irradiation of the nasopharynx

Journal of the National Cancer Institute
D P SandlerG M Matanoski

Abstract

Eighteen to 35 years after admission to a clinic for the prevention of deafness, no increased overall cancer risk could be detected among 904 persons who had been treated with nasopharyngeal radium irradiation when compared with the risk among 2,021 persons who were either treated surgically or not treated at all, although there were differences at specific sites. An increased risk of developing both benign and malignant head and neck tumors was found among irradiated persons. Whereas no one head and neck site showed a statistically significant excess, a slight excess of brain cancer occurred 15-20 years after radium treatment. No increase in thyroid cancer risk was observed, a result possibly attributable to the low radiation doses to this organ, and the relatively small population irradiated.

Related Concepts

Adenoidal Structure
Surface Radiotherapy
Cancer of Neck
Hypertrophy
Structure of Choanae
Radiation-Induced Cancer
Radium
Hearing Impairment

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