PMID: 6401599Mar 15, 1983Paper

Neoplastic angioendotheliomatosis. Histologic, immunohistochemical, and ultrastructural findings in two cases

Cancer
K H Fulling, D J Gersell

Abstract

Two cases of neoplastic angioendotheliomatosis are described. Both patients presented with subacute development of dementia punctuated by focal neurologic signs. Postmortem examination in both cases disclosed a vasculocentric distribution of neoplastic cells in many organs. Two characteristic histologic patterns were seen: (1) distension of vascular spaces by free-floating, intraluminal cells and (2) asymmetric, subendothelial tumor growth. Intravascular tumor and secondary vascular changes were associated with microinfarcts in involved organs. Immunohistochemical localization of factor VIII-related antigen in the neoplastic cells of one case provides evidence for their endothelial origin. The neoplastic cells in both cases exhibited similar but nonspecific ultrastructural features. In addition, dramatic fine structural changes including the acquisition of numerous pinocytotic vesicles and bundles of fine filaments with periodic densities were found in the non-neoplastic endothelial cells.

References

May 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D R Zehr
Nov 1, 1977·Human Pathology·R A Eady, E W Jones
Dec 1, 1979·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L A Sternberger
Jan 1, 1979·Archives of Neurology·C L DolmanA Magil
May 1, 1978·Annals of Neurology·C K PetitoF A Petito
Mar 1, 1977·Stroke; a Journal of Cerebral Circulation·J L ReinglassH Wellman
Jan 1, 1975·Journal of Ultrastructure Research·C C HaudenschildJ Folkman
Nov 1, 1973·The Journal of Clinical Investigation·L W HoyerJ R Hoyer
Nov 1, 1973·The Journal of Clinical Investigation·E A JaffeR L Nachman
May 31, 1974·Acta Neuropathologica·G T Bots
Sep 1, 1971·Archives of Dermatology·M FievezJ Hustin
Sep 1, 1969·The Journal of Cell Biology·G MajnoM Leventhal
Jun 1, 1980·The American Journal of Surgical Pathology·K MukaiW H Burgdorf
Jul 1, 1980·Archives of Dermatology·Y C KauhH A Luscombe
Jul 1, 1965·Neurology·J C STROUTHA ALDRED

❮ Previous
Next ❯

Citations

Jun 17, 1998·Arthritis and Rheumatism·J von KempisH H Peter
Mar 1, 1995·Microscopy Research and Technique·G SrinivasanN Bashirelahi
Jan 1, 1986·Acta Neuropathologica·C L Dolman
Jan 1, 1989·Acta Neuropathologica·C VitalJ Maupetit
Mar 1, 1985·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·T Mannen
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·L Laurino, M Melato
Nov 27, 2004·European Archives of Psychiatry and Clinical Neuroscience·R AlbrechtH A Kretzschmar
May 1, 1991·Journal of the Neurological Sciences·D B WilliamsP M Banks
Jan 1, 1992·Clinical Neurology and Neurosurgery·D LacomisR R Long
Apr 2, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Brigitte K NixonBrian P Rubin
Apr 10, 1986·The New England Journal of Medicine·K SheibaniH Rappaport
Jul 1, 1997·The American Journal of Surgical Pathology·M A RubinN Azumi
Apr 1, 1992·Acta Pathologica Japonica·H UsudaY Ohnishi
Aug 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·R S KnightJ M Theaker
Aug 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·R TorenbeekP van der Valk
Mar 1, 1989·Ultrastructural Pathology·R A Erlandson, D A Filippa
Apr 1, 1987·Pathology, Research and Practice·K RembergerM Haider
Oct 1, 1989·Journal of the American Academy of Dermatology·N PetroffR Tubbs
Jan 1, 1992·Journal of the American Academy of Dermatology·F López-GilP Umbert
Nov 1, 1985·Journal of the American Academy of Dermatology·H W Lim, H M Anderson
Feb 1, 1988·Journal of the American Academy of Dermatology·T G Berger, N A Dawson
Mar 9, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seema BasiAgnes B Fogo
May 13, 2005·Australian Veterinary Journal·L Ridge, G Swinney
Apr 1, 1991·Clinics in Dermatology·P E Swanson, M R Wick
Dec 1, 1986·Histopathology·J M TheakerP Easterbrook
Nov 26, 1997·American Journal of Hematology·E P GaborK E Mercola
Jan 15, 1990·Cancer·S A Yousem, T V Colby

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.