PMID: 8459801Mar 10, 1993Paper

Neoplastic association of enhanced type V collagen production in rat fibrosarcoma

Molecular and Cellular Biochemistry
R AsokanS C Dhar

Abstract

Collagens present in the connective tissues of the extracellular matrix of fibrosarcoma were isolated and characterized. The fibrosarcoma was induced in rats by the administration of 3-methylcholanthrene. The results obtained were compared with normal muscle. An excess amount of type V collagen was found to be produced by the fibrosarcoma tissue compared to the normal muscle. Type V collagen from fibrosarcoma was characterized on the basis of solubility behavior in sodium chloride solutions, electrophoretic mobility on SDS-polyacrylamide gels, elution pattern of phosphocellulose chromatography and amino acid composition.

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Citations

Dec 16, 1998·Eye·A M Abu el-AsrarL Missotten
Feb 15, 2018·Cancer Cell International·Renato F IvanovicSabrina T Reis
Nov 4, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Hasini JayatilakaDenis Wirtz

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