[Neovascular age-related macular degeneration in Germany. Encroachment on the quality of life and the financial implications].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Daniel PauleikhoffXiao Xu

Abstract

Approximately 35,000 cases of neovascular age-related macular degeneration (AMD) occur annually in Germany. The neovascular form of AMD (NV-AMD) is responsible for severe vision loss associated with the disease in 90% of the cases. This study was conducted to assess the humanistic and economic burden of NV-AMD in the German population. A cross-sectional, observational study of subject self-reported functional health, well-being, and disease burden among elderly subjects with (n=83) and without (n=93) NV-AMD in Germany was conducted. Patients participated in telephone surveys involving the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), the EuroQol (EQ-5D), the Hospital Anxiety and Depression Scale (HADS), and also reported history of falls, fractures, and healthcare resource utilization. Furthermore, the healthcare utilization and unit costs for the NV-AMD patients were calculated. The mean age of NV-AMD patients was 77.2 years and 64% were female. NV-AMD patients reported significantly worse vision-related function and overall well-being than controls (adjusted mean scores: NEI-VFQ-25 overall scale: 51.3 vs 96.3; p<0.0001) and significantly more depression symptoms than controls (HADS depression: 6.2 vs. 2.7...Continue Reading

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Citations

May 20, 2014·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C Wolfram, N Pfeiffer
Jan 9, 2013·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·J GibbertS Stock
Feb 6, 2013·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A MielkeS Trauzettel-Klosinski
Aug 23, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alexa Karina KlettnerJohann Roider
Sep 6, 2013·Journal of Medical Economics·Isobel PearsonKim Wittrup-Jensen
Apr 3, 2014·Acta Ophthalmologica·Katharina SchrammMichael J Koss
Jan 16, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Armin Wolf, Anselm Kampik
Sep 19, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christoph HirneissAljoscha S Neubauer
Mar 3, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A S NeubauerA Kampik
Jul 19, 2014·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·B LehmannA Lommatzsch
Sep 8, 2019·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Yuliya ChuvarayanJuliane Köberlein-Neu
Oct 7, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·H Weyer-WendlP Walter
Jun 4, 2021·International Journal of Retina and Vitreous·Sabrina MüllerFocke Ziemssen

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