Nephrogenic Adenoma in the Setting of Refractory Labial Agglutination in an Elderly Woman.

Female Pelvic Medicine & Reconstructive Surgery
Carol Emi BretschneiderMarie Fidela R Paraiso

Abstract

Severe labial agglutination can be refractory to outpatient management and can lead to voiding dysfunction in postmenopausal women. Labial agglutination is often a sequela of long-standing inflammatory processes, which include untreated lichen planus, lichen sclerosus, and atrophic vaginitis. An 82-year-old parous woman presented with severe labial agglutination and complete obstruction of her vaginal introitus, causing obstructive voiding symptoms. She underwent a surgical procedure to release the fused labia. Pathologic evaluation of a vulvar biopsy revealed nephrogenic adenoma, which is an uncommon benign lesion usually presenting in the urinary tract. Refractory, severe labial agglutination in postmenopausal women can lead to significant voiding dysfunction, and the underlying chronic inflammation may result in pathologic changes such as nephrogenic adenoma. Pathologic tissue diagnosis is important to plan appropriate surveillance for patients with this chronic condition.

References

Jan 14, 2012·Journal of the Chinese Medical Association : JCMA·Ching-Hsin ChangKuang-Kuo Chen
Mar 15, 2012·International Journal of Surgical Pathology·Borislav A Alexiev, Charles M LeVea
Aug 14, 2012·Journal of Lower Genital Tract Disease·Jennifer Bradford, Gayle Fischer
Apr 25, 2013·Female Pelvic Medicine & Reconstructive Surgery·George LazarouKaitlyn Mitchell
Apr 2, 2014·Annals of Transplantation : Quarterly of the Polish Transplantation Society·Bolesław KuzakaPiotr Radziszewski
May 4, 2016·Urology·Jennifer GordetskySoroush Rais-Bahrami

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