Nephrogenic adenoma of the bladder: a single institution experience assessing clinical factors

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Yooni YiAnne P Cameron

Abstract

Nephrogenic adenoma (NA) was first described by Davis in 1949 as a "hamartoma" of the bladder. There are many proposed predisposing factors for NA including chronic inflammation, renal transplantation, and bladder cancer. We examined our experience with NA to determine predisposing factors and determine if there was any increased risk for development of subsequent malignancy. All patients with a pathologic diagnosis of bladder NA from 2001-2013 were included. Patient history, clinical factors including possible predisposing factors for NA, and follow-up were reviewed. Among 60 patients, 68% were males with an average age of 61, an average BMI of 28.7, and 60% had a smoking history. In evaluating pro-inflammatory factors, 26.7% underwent either Bacillus Calmette-Guerin or mitomycin C, 30% had recurrent urinary tract infections, and 25% had a history of catheterization. Recurrence of NA after initial resection occurred only in 14.7% of patients who underwent follow-up cystoscopy. A history of concurrent bladder cancer was seen in 41.7% of patients, but there were no cases of de novo bladder cancer diagnosed after NA. To the best of our knowledge, this is the largest series of patients with NA of the bladder. NA occurs in a hetero...Continue Reading

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Citations

Sep 10, 2019·Jornal brasileiro de nefrologia : ʹorgão oficial de Sociedades Brasileira e Latino-Americana de Nefrologia·Cristian V Riella
Apr 18, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Oscar LauciricaMarta Muniesa
Oct 20, 2020·Pathology·Hemamali SamaratungaLars Egevad
Oct 31, 2020·Case Reports in Transplantation·Iftikhar KhanMohammad Al Qahtani
Mar 14, 2020·Actas urologicas españolas·M I Oviedo Ramírez, A Garzón Arana
Apr 27, 2021·Radiology Case Reports·George Koberlein, Martha Munden

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Methods Mentioned

BETA
biopsy

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