Nephrometry score is associated with volume loss and functional recovery after partial nephrectomy

The Journal of Urology
Matthew SimmonsSteven C Campbell

Abstract

Functional volume preservation after partial nephrectomy is a primary determinant of kidney function. We identified tumor features, including R.E.N.A.L. (radius for tumor size as maximal diameter, exophytic/endophytic tumor properties, nearness of deepest portion of tumor to collecting system or sinus, anterior/posterior descriptor and location relative to polar line) and centrality index nephrometry scores, associated with volume loss after partial nephrectomy. A chart and imaging review was done for 237 patients who underwent partial nephrectomy from 2007 to 2010 and met study inclusion criteria. R.E.N.A.L. and centrality index nephrometry scores were measured in all patients. Percent functional volume preservation was estimated a median of 1.4 years after surgery using the cylindrical volume ratio method. Statistical analysis was done to study associations. Independent tumor features associated with percent functional volume preservation included tumor diameter (p < 0.001) and the distance from tumor periphery to kidney center (p = 0.02). R.E.N.A.L. and centrality index scores were associated with percent functional volume preservation (each p < 0.001). Nephrometry scores were also associated with nadir and late percent glom...Continue Reading

References

Feb 14, 2006·The Journal of Urology·Igor FrankInderbir S Gill
Jun 13, 2006·Urology·Ramakrishna VenkateshJaime Landman
Nov 18, 2008·The Journal of Urology·Cheryn SongHanjong Ahn
Jul 21, 2009·The Journal of Urology·David A LifshitzArieh L Shalhav
Mar 20, 2010·The Journal of Urology·Matthew N SimmonsInderbir S Gill
Nov 3, 2010·The Journal of Urology·Mary K SamplaskiMatthew N Simmons
Nov 23, 2010·BJU International·Bryan BrunerMichael L Blute
Dec 21, 2010·BJU International·Matthew H HaynHyung L Kim
Apr 26, 2011·European Urology·Brian F Chapin, Christopher G Wood
May 24, 2011·World Journal of Urology·Eugene K ChaDouglas S Scherr
Jun 18, 2011·The Journal of Urology·Matthew N SimmonsSteven C Campbell
Mar 20, 2012·The Journal of Urology·Matthew N SimmonsSteven C Campbell

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Citations

Jan 13, 2016·Current Urology Reports·Michael J BilesSolomon L Woldu
Jan 8, 2017·Abdominal Radiology·Nicole WakeHersh Chandarana
Apr 28, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Dong Soo ParkJong Jin Oh
Mar 31, 2015·The Journal of Urology·Alexa MeyerJames M McKiernan
Dec 26, 2019·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Amanda E KahnDavid D Thiel
May 14, 2014·ANZ Journal of Surgery·John R KucharczykDaniel Moon
Dec 26, 2018·International Journal of Urology : Official Journal of the Japanese Urological Association·Young Dong YuSangchul Lee
Nov 12, 2014·Scandinavian Journal of Urology·Harry NisenKimmo Taari
Sep 27, 2018·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Alexander SterzikSabine D Brookman-May

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