Nerve-epithelium association in the periodontal ligament of guinea pig teeth

Archives of Oral Biology
Chantha K Jayawardena, Yoshiro Takano

Abstract

Several lines of evidence have suggested that periodontal nerves have other roles besides sensory function. Exploring the distribution pattern of nerves in relation to other structures within the periodontal ligament of various species should be important to understand their roles within the ligament. This study investigated whether any association exists between the nerves and the epithelial cells in the periodontal ligament of continuously erupting guinea pig molars, which show distinct enamel epithelium layers among the cementum pearls. Ten guinea pigs were fixed by vascular perfusion and jaw sections were processed for immunohistochemistry of protein gene product 9.5 (PGP 9.5), growth-associated protein-43 (GAP-43) and glia-specific S-100 protein, and for enzyme histocytochemistry of cholinesterase. Nerves that were immunopositive for the above neuronal markers were located predominantly in the alveolus-related part of the periodontal ligament. Some nerves, immunoreactive for PGP 9.5 and GAP-43, were also found in the tooth-related part (TRP) of the periodontal ligament close to the tooth surface. PGP 9.5-positive nerves in the TRP appeared very thin and terminated by making loops or plexus-like structures in close appositi...Continue Reading

References

Jan 1, 1989·Annual Review of Neuroscience·J H Skene
Feb 1, 1997·Periodontology 2000·W BeertsenJ Sodek
Apr 12, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·T MaedaS Wakisaka
Oct 23, 2002·Archives of Histology and Cytology·Chantha K JayawardenaYoshiro Takano
Feb 1, 2003·Journal of Periodontal Research·Naohiko HasegawaHidemi Kurihara
Jul 24, 2004·Journal of Dental Research·K FujiyamaT Takano-Yamamoto
Apr 21, 2005·Journal of Dental Research·D D Bosshardt

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Citations

Jul 16, 2010·Archives of Oral Biology·T L NandasenaC D Nanayakkara
Oct 9, 2019·Proceedings. Biological Sciences·Louise F MartinMarcus Clauss

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