PMID: 12781910Jun 5, 2003Paper

Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability

Neuroscience Letters
Undine E LangR Hellweg

Abstract

Human nerve growth factor (NGF) serum concentrations were measured in a healthy sample of 126 participants by a modified highly sensitive and specific two-site enzyme immunoassay. The measured NGF concentrations differ considerably from a normal distribution. The median NGF concentration was 19.68 pg/ml with an interquartile range of 11.06-41.74 pg/ml, which means that 50% of the NGF levels are in this range. In our healthy sample, we found no gender differences but a slight age-related decrease of NGF (r=-0.1326, P=0.1560). Moreover intraindividual stability of NGF was examined in ten volunteers, where no significant changes of serum NGF concentrations were detected over 4 weeks. This stability of our repetitive measurements over 4 weeks suggests that this neurotrophin may be an intraindividually solid marker at least in human serum.

References

Oct 25, 1994·Proceedings of the National Academy of Sciences of the United States of America·L AloeP Tirassa
Oct 1, 1996·Proceedings of the National Academy of Sciences of the United States of America·S BoniniL Aloe
Dec 20, 1996·Neuroreport·T SerranoS Armenteros
Apr 20, 2001·Journal of Neuroimmunology·M HadjiconstantinouR Glaser
Apr 2, 2002·The American Journal of Psychiatry·Undine E LangRainer Hellweg

❮ Previous
Next ❯

Citations

Feb 22, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Ying-Xue DongYong-Mei Cha
Oct 22, 2005·Clinical Neuropharmacology·Thomas MüllerRainer Hellweg
Jan 24, 2006·Cephalalgia : an International Journal of Headache·F BlandiniA Leon
Jan 26, 2012·BMC Neuroscience·Alessandro MassellaLuciana Giardino
Dec 18, 2013·Cellular and Molecular Neurobiology·Andrius KaselisSaulius Šatkauskas
Sep 20, 2005·Reproductive Biomedicine Online·Chinmoy K Bose
Dec 9, 2008·Cytokine·Yian GuAlan A Arslan
Jul 22, 2008·Psychoneuroendocrinology·Annemarie HeberleinThomas Hillemacher
Apr 17, 2007·Neuroscience Letters·Maria C Jockers-ScherüblRainer Hellweg
Dec 5, 2006·Journal of Reproductive Immunology·Olaf Schulte-HerbrüggenMarek Lommatzsch
Oct 24, 2006·Progress in Neuro-psychopharmacology & Biological Psychiatry·Maria C Jockers-ScherüblRainer Hellweg
Sep 12, 2008·Journal of Internal Medicine·C DagnellC Olgart Höglund
Feb 20, 2007·Oral Diseases·J-W NamY-K Kim
May 31, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I J WangP C Chen
Mar 1, 2012·Lower Urinary Tract Symptoms·Hann-Chorng Kuo
Aug 2, 2006·Neurobiology of Aging·Andreas A ZiegenhornRainer Hellweg
Aug 22, 2015·Neuropeptides·Dakheel A Al-DakheelMohammed El-Shawarby
Apr 11, 2013·Neuroscience Letters·Anders B KleinJens D Mikkelsen
Jun 19, 2004·Stress : the International Journal on the Biology of Stress·Undine E LangRainer Hellweg
Oct 16, 2016·American Journal of Physiology. Gastrointestinal and Liver Physiology·Amrita AhluwaliaAndrzej S Tarnawski
Jun 21, 2007·International Archives of Allergy and Immunology·O Schulte-HerbrüggenR Hellweg
Nov 21, 2017·The Journal of Laryngology and Otology·I B ArslanA Aslan
Oct 20, 2020·Frontiers in Endocrinology·Ryan E TomlinsonDamian C Genetos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.