Nerve regeneration and wound healing are stimulated and directed by an endogenous electrical field in vivo

Journal of Cell Science
Bing SongColin D McCaig

Abstract

Biological roles for naturally occurring, extracellular physiological electric fields have been proposed over the past century. However, in the molecular era, many biologists presume that electric fields have little physiological relevance because there has been no unequivocal demonstration of their importance at the single-cell level in vivo. We have used an in vivo rat corneal model, which generates its own endogenous electric field and show that nerve sprouting, the direction of nerve growth and the rate of epithelial wound healing are controlled coordinately by the wound-induced electric field.

References

May 1, 1975·The American Journal of Physiology·S D Klyce
Jun 11, 1992·Experimental Eye Research·M ChiangJ W Vanable
Mar 18, 1991·Brain Research. Developmental Brain Research·K B Hotary, K R Robinson
May 1, 1986·The American Journal of Physiology·O A Candia, P Cook
Dec 1, 1983·The American Journal of Physiology·R PatarcaP S Reinach
Mar 11, 1982·The American Journal of Physiology·A T BarkerJ W Vanable
Jan 1, 1982·The Journal of Membrane Biology·S D Klyce, W S Marshall
Feb 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R Shi, R B Borgens
Sep 23, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·C D McCaig, M Zhao
Jan 20, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·D D Sta Iglesia, J W Vanable
Jul 7, 1995·Current Opinion in Ophthalmology·I K Gipson, T Inatomi
Apr 15, 1999·Annual Review of Neuroscience·B K Mueller
Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·M ZhaoC D McCaig
Jul 8, 1999·Current Opinion in Neurobiology·H J Song, M M Poo
Dec 30, 1999·Progress in Retinal and Eye Research·J ImanishiS Kinoshita
Mar 7, 2001·Nature Cell Biology·H Song, M Poo
Apr 23, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Min ZhaoColin D McCaig
Jun 1, 2002·Science·Karen H MartinJ Thomas Parsons
Aug 6, 2002·Nature Neuroscience·Yang XiangShumin Duan
Oct 9, 2002·Proceedings of the National Academy of Sciences of the United States of America·Bing SongColin D McCaig

❮ Previous
Next ❯

Citations

Jun 3, 2005·Bioelectromagnetics·Richard D Saunders, C D McCaig
Jan 6, 2011·Cellular and Molecular Life Sciences : CMLS·Lin CaoMin Zhao
Mar 22, 2013·BioResearch Open Access·Addie HicksJames D Sweeney
May 6, 2008·Tissue Engineering. Part B, Reviews·Grace N Li, Diane Hoffman-Kim
Feb 1, 2011·Tissue Engineering. Part B, Reviews·Li YaoColin D McCaig
Mar 15, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Entong WangMin Zhao
Aug 12, 2010·Journal of Biomaterials Science. Polymer Edition·Y K A LowK W Ng
Mar 29, 2014·PloS One·Joana MonteiroJoaquín Rodríguez-León
May 1, 2009·HFSP Journal·Alice Rodriguez-DiazDaniel P Kiehart
Apr 25, 2014·Advances in Wound Care·Niels Haan, Bing Song
Apr 25, 2014·Advances in Wound Care·Brian Reid, Min Zhao
May 24, 2013·Archives of Dermatological Research·Yen-Kim WonChong-Jin Loy
Jul 12, 2014·Annual Review of Biomedical Engineering·Deanna M ThompsonChristine E Schmidt
Dec 22, 2009·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Hirofumi KaiEiichi Araki
Jan 27, 2016·Journal of Radiation Research·Daryoush Shahbazi-GahroueiNaser Naghdi
Jun 15, 2011·Trends in Cell Biology·Jing Li, Francis Lin
Apr 23, 2010·The Journal of Investigative Dermatology·Aihua GuoMin Zhao
Apr 9, 2008·Journal of Cellular Physiology·Li YaoMin Zhao
Oct 30, 2007·Developmental Neurobiology·Kenneth R Robinson, Peter Cormie
Jul 3, 2010·Journal of Biomedical Materials Research. Part a·R D BreukersG G Wallace
Oct 15, 2010·Journal of Cellular Physiology·Romana KucerovaJ Martin Collinson
Aug 23, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Cheng-Hsien TsaiPen-Hsiu Grace Chao
Jun 15, 2013·Biomaterials·Sarah SundelacruzDavid L Kaplan
Oct 25, 2011·Progress in Retinal and Eye Research·Min ZhaoBrian Reid
Jun 2, 2015·Frontiers in Physiology·Richard H W Funk
Jan 17, 2009·Seminars in Cell & Developmental Biology·Min Zhao
Apr 26, 2008·Developmental Biology·Nathan R Farrar, Gaynor E Spencer
Oct 30, 2015·IEEE Transactions on Bio-medical Engineering·Pragya Jai KumarRebecca Kuntz Willits
Sep 7, 2016·Regenerative Medicine·Jack Finnegan, Hui Ye
Nov 10, 2016·Development·Fernando FerreiraMin Zhao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Bing SongColin D McCaig
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Brian ReidMin Zhao
© 2021 Meta ULC. All rights reserved