Nervous mechanisms of restraint water-immersion stress-induced gastric mucosal lesion.

World Journal of Gastroenterology : WJG
Dong-Qin ZhaoHai-Ji Sun

Abstract

Stress-induced gastric mucosal lesion (SGML) is one of the most common visceral complications after trauma. Exploring the nervous mechanisms of SGML has become a research hotspot. Restraint water-immersion stress (RWIS) can induce GML and has been widely used to elucidate the nervous mechanisms of SGML. It is believed that RWIS-induced GML is mainly caused by the enhanced activity of vagal parasympathetic nerves. Many central nuclei, such as the dorsal motor nucleus of the vagus, nucleus of the solitary tract, supraoptic nucleus and paraventricular nucleus of the hypothalamus, mediodorsal nucleus of the thalamus, central nucleus of the amygdala and medial prefrontal cortex, are involved in the formation of SGML in varying degrees. Neurotransmitters/neuromodulators, such as nitric oxide, hydrogen sulfide, vasoactive intestinal peptide, calcitonin gene-related peptide, substance P, enkephalin, 5-hydroxytryptamine, acetylcholine, catecholamine, glutamate, γ-aminobutyric acid, oxytocin and arginine vasopressin, can participate in the regulation of stress. However, inconsistent and even contradictory results have been obtained regarding the actual roles of each nucleus in the nervous mechanism of RWIS-induced GML, such as the involv...Continue Reading

References

Mar 1, 1992·Progress in Neuro-psychopharmacology & Biological Psychiatry·G B Glavin
Nov 1, 1992·General Pharmacology·G B Glavin
Nov 7, 1991·Nature·K MoriyoshiS Nakanishi
Jan 1, 1991·The American Journal of Physiology·L P XingG Kauffman
Nov 1, 1991·Digestive Diseases and Sciences·P G HenkeR M Sullivan
Sep 1, 1990·Digestive Diseases and Sciences·G B Glavin, S Szabo
Jan 1, 1989·Annals of the New York Academy of Sciences·Y TachéT Ishikawa
Nov 1, 1988·The American Journal of Physiology·A V FergusonJ L Wallace
Jan 1, 1987·The American Journal of Physiology·W B Laughton, T L Powley
Feb 1, 1986·The American Journal of Physiology·T GarrickP Bass
Jul 1, 1985·The American Journal of Physiology·F D PaganiR A Gillis
Sep 1, 1993·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·J GatónA Velasco
Feb 1, 1994·The American Journal of Physiology·L E HierlihyA V Ferguson
Jan 1, 1994·Annual Review of Biophysics and Biomolecular Structure·S Nakanishi, M Masu
Jan 1, 1993·Journal of Physiology, Paris·M Grassi, F Drago
May 1, 1997·The American Journal of Physiology·Z K KrowickiP J Hornby
Apr 1, 1997·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·S Evangelista, D Renzi
Jul 4, 1998·Brain Research. Brain Research Reviews·S NakanishiM Okada
Aug 8, 1998·The American Journal of Physiology·L P FilaretovaG B Makara
Feb 3, 1999·Annals of the New York Academy of Sciences·N TunçelM Tunçel
Mar 22, 2002·Clinical and Experimental Pharmacology & Physiology·Yoshiji Ohta, Keiji Nishida
May 23, 2002·The Journal of Pharmacology and Experimental Therapeutics·Brigitta M PeskarBernhard A Peskar
Jun 5, 2002·Neuroscience Letters·O LiubashinaS Khotiantsev
Feb 3, 2004·Current Topics in Medicinal Chemistry·K Gyires
Mar 25, 2004·Clinical Therapeutics·Mitchell J Spirt
Feb 8, 2006·Annual Review of Physiology·R Alberto TravagliRichard C Rogers

❮ Previous
Next ❯

Citations

Aug 31, 2021·Autonomic Neuroscience : Basic & Clinical·Guillaume LamotteEduardo E Benarroch

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Basal Forebrain- Circuits

Basal forebrain is a region in the brain important for production of acetylcholine and is the major cholinergic output of the CNS. Discover the latest research on circuits in the basal forebrain here.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.