Networking chemical robots for reaction multitasking

Nature Communications
Dario CaramelliLeroy Cronin

Abstract

The development of the internet of things has led to an explosion in the number of networked devices capable of control and computing. However, whilst common place in remote sensing, these approaches have not impacted chemistry due to difficulty in developing systems flexible enough for experimental data collection. Herein we present a simple and affordable (<$500) chemistry capable robot built with a standard set of hardware and software protocols that can be networked to coordinate many chemical experiments in real time. We demonstrate how multiple processes can be done with two internet-connected robots collaboratively, exploring a set of azo-coupling reactions in a fraction of time needed for a single robot, as well as encoding and decoding information into a network of oscillating reactions. The system can also be used to assess the reproducibility of chemical reactions and discover new reaction outcomes using game playing to explore a chemical space.

References

Nov 8, 2008·Physical Chemistry Chemical Physics : PCCP·Slavica M BlagojevićLjiljana Z Kolar-Anić
Jan 5, 2010·Chemical & Pharmaceutical Bulletin·Kazuhiro MachidaTakashi Takahashi
Apr 24, 2012·Nature Chemistry·Mark D SymesLeroy Cronin
May 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Mark Schrope
Sep 13, 2014·Chemistry : a European Journal·Rabih MakkiJuan Perez-Mercader
Dec 18, 2014·Nature Chemistry·Ryan A SkiltonMartyn Poliakoff
Apr 15, 2016·Nature·Jens Jakob W H SørensenJacob F Sherson
May 27, 2016·Nature·Monya Baker
Feb 2, 2017·Beilstein Journal of Organic Chemistry·Philip J KitsonLeroy Cronin
Feb 6, 2017·Nature·Jeffrey M Perkel

❮ Previous
Next ❯

Citations

Dec 17, 2019·Astrobiology·Bruce Damer, David Deamer
Apr 30, 2019·Advanced Materials·Daniela S MattesFrank Breitling
Jun 14, 2019·Nature·Ian W Davies
Sep 18, 2020·Chemistry : a European Journal·Chun-Wei ChangCheng-Chung Wang
Feb 27, 2021·Angewandte Chemie·Chun-Wei ChangCheng-Chung Wang
Nov 6, 2018·The Journal of Physical Chemistry. a·Jiagen LiXi Zhu
Feb 14, 2019·The Journal of Physical Chemistry. a·Yi-Pei LiWilliam H Green
Aug 14, 2020·Chemical Reviews·Gurpur Rakesh D Prabhu, Pawel L Urban

❮ Previous
Next ❯

Software Mentioned

Python
BoW
pcDuino
Linux Ubuntu

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Trends in Biochemical Sciences
U R Smith
Scientific American
Neil GershenfeldDanny Cohen
© 2022 Meta ULC. All rights reserved