Networks of face-to-face social contacts in Niakhar, Senegal

PloS One
Gail E PotterM Elizabeth Halloran

Abstract

We present the first analysis of face-to-face contact network data from Niakhar, Senegal. Participants in a cluster-randomized influenza vaccine trial were interviewed about their contact patterns when they reported symptoms during their weekly household surveillance visit. We employ a negative binomial model to estimate effects of covariates on contact degree. We estimate the mean contact degree for asymptomatic Niakhar residents to be 16.5 (95% C.I. 14.3, 18.7) in the morning and 14.8 in the afternoon (95% C.I. 12.7, 16.9). We estimate that symptomatic people make 10% fewer contacts than asymptomatic people (95% C.I. 5%, 16%; p = 0.006), and those aged 0-5 make 33% fewer contacts than adults (95% C.I. 29%, 37%; p < 0.001). By explicitly modelling the partial rounding pattern observed in our data, we make inference for both the underlying (true) distribution of contacts as well as for the reported distribution. We created an estimator for homophily by compound (household) membership and estimate that 48% of contacts by symptomatic people are made to their own compound members in the morning (95% CI, 45%, 52%) and 60% in the afternoon/evening (95% CI, 56%, 64%). We did not find a significant effect of symptom status on compound...Continue Reading

References

May 1, 1982·American Journal of Epidemiology·I M LonginiJ P Fox
May 14, 2004·Nature·Stephen EubankNan Wang
Aug 5, 2005·Science·Ira M LonginiM Elizabeth Halloran
Aug 5, 2005·Nature·Neil M FergusonDonald S Burke
Apr 6, 2006·Proceedings of the National Academy of Sciences of the United States of America·Timothy C GermannCatherine A Macken
Apr 28, 2006·Nature·Neil M FergusonDonald S Burke
Jul 20, 2006·Journal of the Royal Society, Interface·Matt J Keeling, Ken T D Eames
Mar 23, 2007·The Lancet Infectious Diseases·Gabrielle BrankstonMichael Gardam
Feb 16, 2008·BMC Public Health·Laura M Glass, Robert J Glass
Mar 6, 2008·Journal of the Royal Society, Interface·Jonathan M ReadW John Edmunds
Mar 12, 2008·Proceedings of the National Academy of Sciences of the United States of America·M Elizabeth HalloranPhilip Cooley
Mar 28, 2008·PLoS Medicine·Joël MossongW John Edmunds
Oct 14, 2008·The Journal of Infection·Thomas P Weber, Nikolaos I Stilianakis
Apr 28, 2009·The Lancet Infectious Diseases·Justin LesslerDerek A T Cummings
Jul 1, 2009·BMJ : British Medical Journal·Jonathan A C SterneJames R Carpenter
Aug 15, 2009·American Journal of Epidemiology·Nicole E BastaIra M Longini
Oct 30, 2009·Proceedings. Biological Sciences·Stefano Merler, Marco Ajelli
Feb 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Simon CauchemezUNKNOWN Pennsylvania H1N1 working group
Jul 9, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Richard A Stein
Aug 23, 2011·PloS One·Juliette StehléPhilippe Vanhems
May 1, 2006·Journal of the Royal Statistical Society. Series C, Applied Statistics·Yang YangM Elizabeth Halloran
May 29, 2012·The Annals of Applied Statistics·Gail E PotterM Elizabeth Halloran
Sep 26, 2013·International Journal of Epidemiology·Valerie DelaunayCheikh Sokhna
Oct 9, 2013·American Journal of Epidemiology·Kim Van KerckhoveKen T D Eames
Mar 13, 2014·BMC Infectious Diseases·Timo SmieszekMarcel Salathé
Apr 29, 2014·PloS One·Arkadiusz StopczynskiSune Lehmann
May 3, 2014·Proceedings. Biological Sciences·Jonathan M ReadDerek A T Cummings
Sep 17, 2014·PloS One·Julie Fournet, Alain Barrat
Apr 7, 2015·Epidemics·Lorenzo PellisPieter Trapman
Oct 16, 2015·Cell Host & Microbe·Gary WongGeorge F Gao
Nov 4, 2015·BMC Infectious Diseases·David A RollsJodie McVernon

❮ Previous
Next ❯

Citations

Nov 10, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mbayame Nd NiangJohn C Victor

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT00893906

Software Mentioned

MIcombine
R
mitools
POLYMOD
numDeriv

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.