Neural cell types surviving congenital sensory deprivation in the optic lobes of Drosophila melanogaster

Developmental Biology
K F Fischbach

Abstract

Golgi staining of neuronal cell types in the optic lobe rudiments of adult eyeless flies of the sine oculis (so) mutant of Drosophila melanogaster reveals partial independence of optic lobe's development from compound eye formation. (1) Differentiation and maintenance of many neuronal cell types of medulla and lobular complex do not require innervation of the medulla from the retina and the lamina. Neurons derived from the outer and inner optic anlage have been found in adult eyeless flies. (2) The rudiments of ipsilateral medulla, lobula, and lobular plate are isotopically connected with each other. (3) Stratification of the lobular complex is retained. (4) Equivalent parts of the dorsal lobulae are connected by heterolateral small field neurons. (5) The shapes of many tangential neurons of the medulla show sprouting and compensatory innervation of the lobular complex. The basic results reported here for eyeless flies have many parallels in what is known about anophthalmic mice.

References

Jul 20, 1976·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·I A Meinertzhagen
Dec 13, 1977·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·N J Strasufeld, K Hausen
Jan 1, 1978·Developmental Biology·E M Meyerowitz, D R Kankel
Aug 1, 1979·Neuroscience Letters·P GodementM Imbert
Aug 16, 1976·Cell and Tissue Research·R Pierantoni
Feb 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·V LoprestiC Levinthal
Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·V LoprestiC Levinthal
Feb 20, 1981·The Journal of Comparative Neurology·P L Donaldson, R K Josephson
Jan 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M J KatzI R Kaiserman-Abramof
Feb 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·K F Fischbach, M Heisenberg
Jul 1, 1978·Neuroscience Letters·K MøllgårdU Stenevi
Apr 21, 1970·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·N J Strausfeld, A D Blest
Apr 21, 1970·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·N J Strausfeld

❮ Previous
Next ❯

Citations

Feb 1, 1993·Current Opinion in Neurobiology·S Kunes, H Steller
Dec 7, 2002·Gene·Bret A Payseur, Michael W Nachman
May 17, 2012·Development, Growth & Differentiation·Yu ToganeHidenobu Tsujimura
Apr 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·Y Rao, S L Zipursky
Dec 1, 1994·Neuron·H Steller, M E Grether
Mar 25, 2014·Journal of Neurogenetics·Charlotte Helfrich-Förster
Jun 11, 2014·Journal of Neurogenetics·Holger Apitz, Iris Salecker
Jun 6, 2000·Developmental Biology·P H TaghertP S Jacobs
Jul 1, 1989·Journal of Neurobiology·I A Meinertzhagen
Sep 30, 2017·Annual Review of Genetics·Michael PerryClaude Desplan
Jun 28, 2006·The Journal of Comparative Neurology·Hideo Otsuna, Kei Ito
Jan 10, 2009·Journal of Neurogenetics·Ian A MeinertzhagenChi-Hon Lee
Jun 1, 1991·Molecular & General Genetics : MGG·H MatsubayashiY N Tobari
Mar 12, 2021·Arthropod Structure & Development·Nicholas J Strausfeld, Briana Olea-Rowe
Mar 13, 2021·Arthropod Structure & Development·Nicholas J Strausfeld
Mar 9, 2019·Current Opinion in Neurobiology·Maximilien Courgeon, Claude Desplan
Jun 30, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jennifer Malin, Claude Desplan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.