Neural coding of sound intensity and loudness in the human auditory system.

Journal of the Association for Research in Otolaryngology : JARO
Markus Röhl, Stefan Uppenkamp

Abstract

Inter-individual differences in loudness sensation of 45 young normal-hearing participants were employed to investigate how and at what stage of the auditory pathway perceived loudness, the perceptual correlate of sound intensity, is transformed into neural activation. Loudness sensation was assessed by categorical loudness scaling, a psychoacoustical scaling procedure, whereas neural activation in the auditory cortex, inferior colliculi, and medial geniculate bodies was investigated with functional magnetic resonance imaging (fMRI). We observed an almost linear increase of perceived loudness and percent signal change from baseline (PSC) in all examined stages of the upper auditory pathway. Across individuals, the slope of the underlying growth function for perceived loudness was significantly correlated with the slope of the growth function for the PSC in the auditory cortex, but not in subcortical structures. In conclusion, the fMRI correlate of neural activity in the auditory cortex as measured by the blood oxygen level-dependent effect appears to be more a linear reflection of subjective loudness sensation rather than a display of physical sound pressure level, as measured using a sound-level meter.

References

Nov 1, 1990·Journal of Experimental Psychology. Human Perception and Performance·D Algom, L E Marks
Feb 1, 1970·The Quarterly Journal of Experimental Psychology·S D Stephens
Jun 1, 1994·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·U HegerlD Mrowinski
Oct 27, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C R GenoveseW F Eddy
Nov 28, 1997·The Journal of the Acoustical Society of America·C Zhang, F G Zeng
Jul 23, 1998·Human Brain Mapping·A R GuimaraesR M Weisskoff
Sep 18, 1998·Neuropsychologia·L JänckeH W Müller-Gärtner
Feb 9, 1999·Human Brain Mapping·W B EdmisterR M Weisskoff
Apr 9, 1999·Human Brain Mapping·D A HallR W Bowtell
Feb 19, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Y YangD A Silbersweig
Jul 14, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G H GloverD Ress
Apr 28, 2001·The Journal of the Acoustical Society of America·D A HallR W Bowtell
May 23, 2001·Nature Neuroscience·T D GriffithsR D Patterson
May 8, 2002·Nature Reviews. Neuroscience·Matthew BrettAdrian M Owen
Jul 12, 2002·Journal of Magnetic Resonance Imaging : JMRI·Deniz BilecenErich Seifritz
Sep 3, 2002·Hearing Research·Heledd C HartDeborah A Hall
Apr 19, 2003·Journal of Computer Assisted Tomography·Katie J LasotaRobert W Prost
Feb 24, 2004·Annual Review of Physiology·Nikos K Logothetis, Brian A Wandell
Jul 30, 2005·NeuroImage·Dave R M LangersWalter H Backes
Apr 29, 2006·Hearing Research·Irina S Sigalovsky, Jennifer R Melcher
Jan 24, 2007·NeuroImage·Bertrand ThirionJean-Baptiste Poline
Jan 27, 2007·NeuroImage·Dave R M LangersWalter H Backes
Oct 24, 2007·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Georg JuckelDan Rujescu
Feb 6, 2008·The Journal of the Acoustical Society of America·Jesko L Verhey, Michael Uhlemann
Jun 6, 2008·The Journal of the Acoustical Society of America·Daniel MenzelJürgen Hellbrück
Nov 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Ann K HarveyRichard G Wise
Dec 9, 2008·Current Biology : CB·Katharina von KriegsteinT D Griffiths
Feb 6, 2009·Ear and Hearing·Michael Epstein, Mary Florentine
Apr 28, 2009·Nature Neuroscience·Nikolaus KriegeskorteChris I Baker
Jul 21, 2009·NeuroImage·Stephan M A ErnstJesko L Verhey
Jan 20, 2010·Psychiatry Research·Markus Röhl, Stefan Uppenkamp
Sep 4, 2010·Human Brain Mapping·Markus RöhlStefan Uppenkamp

❮ Previous
Next ❯

Citations

Jun 21, 2013·Der Radiologe·C M KrickW Reith
Feb 2, 2016·The Journal of the Acoustical Society of America·Suyash Narendra JoshiWalt Jesteadt
Aug 27, 2013·Hearing Research·Stefan Uppenkamp, Markus Röhl
Nov 12, 2014·Frontiers in Neurology·Benjamin D AuerbachRichard J Salvi
May 21, 2016·Frontiers in Neuroscience·Andrew ThwaitesBrian C J Moore
Jun 17, 2016·Cognitive Neuropsychology·Jeffrey R BinderRutvik H Desai
Oct 4, 2016·Hearing Research·Maaike Van EeckhoutteTom Francart
Jan 19, 2019·Biomedizinische Technik. Biomedical Engineering·Robert KühlerChristian Koch
Sep 6, 2018·The Journal of the Acoustical Society of America·Iko PieperStephan D Ewert
Apr 11, 2018·Journal of the Association for Research in Otolaryngology : JARO·Stefan WederColette McKay
Dec 8, 2020·Neuroscience and Biobehavioral Reviews·Zachary J WilliamsTiffany G Woynaroski
Feb 25, 2021·Experimental Physiology·Manuel Muñoz-CaracuelCarlos M Gómez
May 6, 2021·Zeitschrift für medizinische Physik·Stefan Uppenkamp

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.