Neural control of hepatic osmolytes and parenchymal cell hydration

The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology
Dieter Häussinger

Abstract

Liver cell function is strongly influenced by cell hydration and osmolyte content via osmosensing and osmosignaling pathways. Electrical stimulation of hepatic nerves increases the hepatocellular hydration state via an alpha-adrenergic mechanism, promotes taurine release from parenchymal cells and myo-inositol release from hepatic stellate cells. Although changes in liver cell hydration and osmolyte content are known regulators of liver cell function, the functional relevance and integration of nerve-stimulation-dependent alterations of liver cell volume and osmolyte content in the overall hepatic response to towards signals from the nervous system remains to be established.

References

Oct 1, 1976·The American Journal of Physiology·A AdachiH L Jacobs
Oct 1, 1992·The Biochemical Journal·B StollD Häussinger
Oct 1, 1992·Trends in Pharmacological Sciences·D Häussinger, F Lang
Nov 1, 1992·Physiology & Behavior·M Kobashi, A Adachi
Jul 15, 1992·European Journal of Biochemistry·A GardemannK Jungermann
May 20, 1991·FEBS Letters·D HäussingerW Gerok
Nov 15, 1991·The Biochemical Journal·S vom DahlD Häussinger
Dec 12, 1991·Biochimica Et Biophysica Acta·D Häussinger, F Lang
Oct 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F LangD Häussinger
Jul 15, 1991·European Journal of Biochemistry·C HallbruckerD Häussinger
Nov 13, 1990·European Journal of Biochemistry·D HüssingerW Gerok
Aug 1, 1989·The American Journal of Physiology·M E Chamberlin, K Strange
May 1, 1980·European Journal of Biochemistry·M Althaus-SalzmannA Jakob
Sep 24, 1982·Science·P H YanceyG N Somero
Jun 1, 1981·Pflügers Archiv : European journal of physiology·E M Tyryshkina Finkinstein YaD
Aug 1, 1995·Current Opinion in Cell Biology·H M Kwon, J S Handler
Sep 1, 1994·Frontiers in Neuroendocrinology·C W BourqueD Richard
Aug 18, 1994·The New England Journal of Medicine·J H LeeB D Ross
Feb 1, 1996·The Biochemical Journal·D Häussinger
Feb 1, 1996·The Journal of Nutrition·S Vom Dahl, D Häussinger
Nov 15, 1996·The Biochemical Journal·F SchliessD Häussinger
Jan 1, 1996·Annual Review of Cell and Developmental Biology·E Ruoslahti
Feb 1, 1997·The Biochemical Journal·U WarskulatD Häussinger
Jan 1, 1997·Annual Review of Physiology·D E Ingber
Jun 1, 1997·Journal of Hepatology·U WarskulatD Häussinger
Feb 11, 1998·Physiological Reviews·F LangD Häussinger
Feb 14, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C WeikD Häussinger
Mar 21, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M WettsteinD Häussinger
Aug 29, 1998·Journal of Hepatology·J H HenriksenN J Christensen
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A K KurzD Häussinger
Dec 16, 1998·Journal of the Autonomic Nervous System·A RemauryA Parini
Dec 24, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T Peters-RegehrD Häussinger

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Citations

May 7, 2010·Journal of Inherited Metabolic Disease·Per Magne Ueland
Jun 23, 2006·Journal of Medicinal Chemistry·Jiri JiracekTimothy A Garrow
Jul 18, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Matthias BehrendsClaus U Niemann
Mar 30, 2010·Clinical Biochemistry·Michael Lever, Sandy Slow
Jan 4, 2015·The Journal of Surgical Research·Apostolos N KandilisDina G Tiniakos
Feb 27, 2008·Journal of Cellular Physiology·Rodrigo FrancoLenin D Ochoa de la Paz

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