Neural Correlates of Empathy with Pain Show Habituation Effects. An fMRI Study

PloS One
Mira A PreisAntonia Barke

Abstract

Neuroimaging studies have demonstrated that the actual experience of pain and the perception of another person in pain share common neural substrates, including the bilateral anterior insular cortex and the anterior midcingulate cortex. As many fMRI studies include the exposure of participants to repeated, similar stimuli, we examined whether empathic neural responses were affected by habituation and whether the participants' prior pain experience influenced these habituation effects. In 128 trials (four runs), 62 participants (31 women, 23.0 ± 4.2 years) were shown pictures of hands exposed to painful pressure (pain pictures) and unexposed (neutral pictures). After each trial, the participants rated the pain of the model. Prior to the experiment, participants were either exposed to the same pain stimulus (pain exposure group) or not (touch exposure group). In order to assess possible habituation effects, linear changes in the strength of the BOLD response to the pain pictures (relative to the neutral pictures) and in the ratings of the model's pain were evaluated across the four runs. Although the ratings of the model's pain remained constant over time, we found neural habituation in the bilateral anterior/midinsular cortex, t...Continue Reading

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Citations

Feb 16, 2016·Neuroscience and Biobehavioral Reviews·Viviana Betti, Salvatore Maria Aglioti
May 9, 2016·Experimental Brain Research·Michel-Pierre CollPhilip L Jackson
May 12, 2017·Journal of Advanced Nursing·Philip L JacksonKenneth M Prkachin
May 5, 2018·Frontiers in Psychology·James W H Sonne, Don M Gash
Jul 16, 2020·Soa--chʻŏngsonyŏn Chŏngsin Ŭihak = Journal of Child & Adolescent Psychiatry·Eun Jin KimJeonghwan Lee

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Methods Mentioned

BETA
SMA
imaging techniques

Software Mentioned

Brain Voyager QX
SPSS

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