Neural correlates of mentalizing-related computations during strategic interactions in humans.

Proceedings of the National Academy of Sciences of the United States of America
Alan N HamptonJohn P O'Doherty

Abstract

Competing successfully against an intelligent adversary requires the ability to mentalize an opponent's state of mind to anticipate his/her future behavior. Although much is known about what brain regions are activated during mentalizing, the question of how this function is implemented has received little attention to date. Here we formulated a computational model describing the capacity to mentalize in games. We scanned human subjects with functional MRI while they participated in a simple two-player strategy game and correlated our model against the functional MRI data. Different model components captured activity in distinct parts of the mentalizing network. While medial prefrontal cortex tracked an individual's expectations given the degree of model-predicted influence, posterior superior temporal sulcus was found to correspond to an influence update signal, capturing the difference between expected and actual influence exerted. These results suggest dissociable contributions of different parts of the mentalizing network to the computations underlying higher-order strategizing in humans.

References

Sep 15, 2001·Science·J D GreeneJ D Cohen
Sep 20, 2001·Proceedings of the National Academy of Sciences of the United States of America·K McCabeT Trouard
May 22, 2002·Neural Computation·Kenji DoyaMitsuo Kawato
Jul 24, 2002·Brain : a Journal of Neurology·S BerthozR J Dolan
Aug 10, 2002·NeuroImage·Helen L GallagherChristopher D Frith
Feb 14, 2003·Trends in Cognitive Sciences·Helen L. Gallagher, Christopher D. Frith
Mar 18, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Robert T SchultzPawel Skudlarski
Apr 12, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Uta Frith, Christopher D Frith
Apr 30, 2003·Neuron·John P O'DohertyRaymond J Dolan
Apr 30, 2003·Neuron·Samuel M McClureP Read Montague
Mar 9, 2004·Nature Neuroscience·Dominic J BarracloughDaeyeol Lee
Jun 11, 2004·Nature·Ben SeymourRichard S Frackowiak
Jul 28, 2004·NeuroImage·James K RillingJonathan D Cohen
Oct 16, 2004·Science·Paul W Glimcher, Aldo Rustichini
Aug 13, 2005·Brain Research. Cognitive Brain Research·Daeyeol LeeDominic J Barraclough
Jan 10, 2006·Science·Colin F Camerer, Ernst Fehr
Mar 23, 2006·Nature Reviews. Neuroscience·David M Amodio, Chris D Frith
Jun 17, 2006·Annual Review of Neuroscience·P Read MontagueJonathan D Cohen
May 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·Terry LohrenzP Read Montague

❮ Previous
Next ❯

Citations

Nov 14, 2013·Nature Communications·Matthew A J Apps, Manos Tsakiris
Dec 25, 2012·Nature Neuroscience·Steve W C ChangMichael L Platt
Jul 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·Christopher J BurkeWolfram Schultz
Sep 8, 2011·Proceedings of the National Academy of Sciences of the United States of America·Nadège BaultGiorgio Coricelli
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Lusha ZhuMing Hsu
Dec 17, 2009·Brain : a Journal of Neurology·Michael V LombardoSimon Baron-Cohen
Apr 25, 2013·Brain : a Journal of Neurology·Paula M GromannLydia Krabbendam
Mar 24, 2011·Cerebral Cortex·Ullrich WagnerPatrik Vuilleumier
Mar 24, 2009·Social Cognitive and Affective Neuroscience·Wouter van den BosEveline A Crone
May 27, 2010·Social Cognitive and Affective Neuroscience·Shinsuke SuzukiEizo Akiyama
Oct 3, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Frank KruegerKevin McCabe
Dec 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Uta Frith, Chris Frith
Apr 12, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Bahador BahramiChris Frith
May 30, 2009·Science·Timothy E J BehrensMatthew F S Rushworth
Jun 24, 2011·Journal of Neurophysiology·Klaus WunderlichJohn P O'Doherty
Aug 5, 2011·Journal of Cognitive Neuroscience·Jeffrey C CooperJohn P O'Doherty
Dec 30, 2008·PLoS Computational Biology·Wako YoshidaKarl J Friston
Oct 27, 2010·PLoS Computational Biology·Misha KoshelevP Read Montague
Dec 11, 2013·PloS One·Ali MahmoodiBahador Bahrami
Feb 8, 2014·PloS One·Marie DevaineJean Daunizeau
Jul 2, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wako YoshidaRay J Dolan
Oct 12, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tao GaoGregory McCarthy
Nov 9, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jeffrey C CooperJohn P O'Doherty
Nov 11, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Guillermo HorgaBradley S Peterson
Apr 8, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nicholas D WrightRaymond J Dolan
Apr 8, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Dylan Alexander Simon, Nathaniel D Daw
Jul 26, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jérôme SalletMatthew F Rushworth
Aug 13, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wako YoshidaRaymond J Dolan
Nov 3, 2010·Proceedings of the National Academy of Sciences of the United States of America·Meghana A BhattP Read Montague
May 28, 2009·Proceedings of the National Academy of Sciences of the United States of America·Giorgio Coricelli, Rosemarie Nagel
Dec 22, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jian LiElizabeth A Phelps
Jan 15, 2013·Social Cognitive and Affective Neuroscience·Dominic S Fareri, Mauricio R Delgado
Jul 6, 2014·Nature Reviews. Neuroscience·Christian C Ruff, Ernst Fehr
Sep 9, 2010·Annual Review of Psychology·James K Rilling, Alan G Sanfey
Aug 16, 2011·Annual Review of Psychology·Chris D Frith, Uta Frith
Sep 23, 2014·Science·Hyojung SeoDaeyeol Lee
Dec 18, 2013·PLoS Computational Biology·Aaron M Bornstein, Nathaniel D Daw

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