Neural correlates of reward-related response tendencies in an equiprobable Go/NoGo task

Cognitive, Affective & Behavioral Neuroscience
Onur AsciRuth M Krebs

Abstract

Previous research has shown that motivational signals bias action over inaction, which may be due to putative inherent valence-action mappings, similar to those observed in the emotional domain. In the present functional magnetic resonance imaging (fMRI) study we sought to investigate the neural underpinnings of such reward-related response tendencies, and in particular, how valence-action compatibility effects arising from predominant response tendencies are reflected at the neural level, and whether overlapping emotional valence amplifies these effects. To this end, we employed an equiprobable (50:50) Go/NoGo task in which reward (reward/no-reward) and response mode (Go/NoGo) were signaled by orthogonal features of number targets that were overlaid on emotional images (positive, neutral, negative). Reward-related targets led to response facilitation (faster Go responses) and impairment in withholding responses (more NoGo commission errors), consistent with a reward-induced action bias. This pattern was paralleled by modulations in the left dorsolateral prefrontal cortex (dlPFC), with increased activity in no-reward as compared to reward-related Go trials, and the reversed pattern in NoGo trials. Albeit being processed in vent...Continue Reading

References

Apr 3, 2001·Annual Review of Neuroscience·E K Miller, J D Cohen
Sep 25, 2001·Behavioural Neurology·Chris Rorden, Matthew Brett
Aug 15, 2002·Proceedings of the National Academy of Sciences of the United States of America·L PessoaL G Ungerleider
Nov 15, 2003·Science·Etienne KoechlinFrédérique Kouneiher
Mar 31, 2004·Trends in Cognitive Sciences·Adam R AronRussell A Poldrack
Jul 9, 2005·Current Opinion in Neurology·Brian Knutson, Jeffrey C Cooper
Aug 19, 2007·Journal of Experimental Psychology. General·Pablo GomezManuel Perea
Apr 28, 2009·Nature Neuroscience·Nikolaus KriegeskorteChris I Baker
May 19, 2009·Trends in Neurosciences·Emrah DüzelPhilippe N Tobler
Nov 3, 2009·Neuropsychologia·Srikanth Padmala, Luiz Pessoa
Aug 20, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Clayton HickeyJan Theeuwes
Sep 23, 2010·Frontiers in Neuroscience·Luiz Pessoa, Jan B Engelmann
Apr 2, 2011·Journal of Cognitive Neuroscience·Srikanth Padmala, Luiz Pessoa
May 27, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marc Guitart-MasipEmrah Duzel
Apr 25, 2012·Proceedings of the National Academy of Sciences of the United States of America·Marc Guitart-MasipRaymond J Dolan
Aug 28, 2012·Cognition·Carsten N BoehlerRuth M Krebs
Feb 19, 2013·Neuroscience and Biobehavioral Reviews·Guillaume SescousseJean-Claude Dreher
Apr 3, 2013·Social Cognitive and Affective Neuroscience·Jong Moon ChoiLuiz Pessoa
Jun 19, 2013·Neuropsychologia·Kesong HuLuiz Pessoa
Jan 15, 2014·Current Biology : CB·Scott M FreemanAdam R Aron
Jan 23, 2014·Cognitive, Affective & Behavioral Neuroscience·Carsten N BoehlerRuth M Krebs
Jun 13, 2014·Cognitive, Affective & Behavioral Neuroscience·Todd S BraverUNKNOWN MOMCAI group
Aug 31, 2014·Brain Research·Brian A AndersonSteven Yantis
Sep 25, 2014·Annual Review of Psychology·Matthew Botvinick, Todd Braver
Jan 21, 2015·Cerebral Cortex·Joset A EtzelTodd S Braver
Aug 8, 2015·Social Cognitive and Affective Neuroscience·Ping WeiLiyan Ji
Mar 1, 2011·Wiley Interdisciplinary Reviews. Cognitive Science·K Richard RidderinkhofWery P M van den Wildenberg
Jul 1, 2016·Proceedings of the National Academy of Sciences of the United States of America·Anders EklundHans Knutsson
Jul 17, 2016·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Giorgio BergaminiChristopher R Pryce
Jan 9, 2017·Trends in Cognitive Sciences·Hans AlvesChristian Unkelbach
Feb 6, 2017·Social Cognitive and Affective Neuroscience·Richard B LopezTodd F Heatherton
May 26, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·G DongM N Potenza
Nov 2, 2017·Human Brain Mapping·Guillaume Flandin, Karl J Friston

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Citations

Jan 22, 2020·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Gerard Derosiere, Julie Duque
May 28, 2019·Cognitive, Affective & Behavioral Neuroscience·Marie T Banich, Stan Floresco
Jun 8, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Vincent HoofsRuth M Krebs
Jun 27, 2021·Human Brain Mapping·Bernadette HippmannSarah Jessen
Jul 27, 2021·Neuroscience and Biobehavioral Reviews·S J S IsherwoodB U Forstmann

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