Neural Correlates of Transient Mal de Debarquement Syndrome: Activation of Prefrontal and Deactivation of Cerebellar Networks Correlate With Neuropsychological Assessment

Frontiers in Neurology
Seung-Ho JeonMarianne Dieterich

Abstract

Background: Mal de debarquement syndrome (MdDS) is characterized by a subjective perception of self-motion after exposure to passive motion, mostly after sea travel. A transient form of MdDS (t-MdDS) is common in healthy individuals without pathophysiological certainty. In the present cross-sectional study, the possible neuropsychiatric and functional neuroimaging changes in local fishermen with t-MdDS were evaluated. Methods: The present study included 28 fishermen from Buan County in South Korea; 15 (15/28, 53.6%) participants experienced t-MdDS for 1-6 h, and 13 were asymptomatic (13/28, 46.4%). Vestibular function tests were performed using video-oculography, the video head impulse test, and ocular and cervical vestibular-evoked myogenic potentials. Visuospatial function was also assessed by the Corsi block test. Brain imaging comprised structural MRI, resting-state functional MRI, and [18F]FDG PET scans. Results: The results of vestibular function tests did not differ between the fishermen with and those without t-MdDS. However, participants with t-MdDS showed better performance in visuospatial memory function than those without t-MdDS (6.40 vs. 5.31, p-value = 0.016) as determined by the Corsi block test. Structural brain...Continue Reading

References

Apr 2, 1979·Experimental Brain Research·T RaphanB Cohen
Feb 29, 1992·BMJ : British Medical Journal·C R GordonI Doweck
Jul 1, 1987·American Journal of Otolaryngology·J J Brown, R W Baloh
Jan 22, 1993·The Journal of Comparative Neurology·N H BarmackH Shojaku
Sep 1, 1994·Journal of Neurophysiology·D E Angelaki, B J Hess
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Jun 19, 1996·Annals of the New York Academy of Sciences·H Cohen
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
Jun 19, 2002·Experimental Brain Research·Theodore Raphan, Bernard Cohen
Jun 5, 2003·Experimental Brain Research·Mingjia DaiBernard Cohen
May 25, 2004·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Susanne M Morton, Amy J Bastian
Sep 2, 2005·Nature Reviews. Neuroscience·Morten L Kringelbach
Apr 3, 2007·Journal of Neurology·Laura Moeller, Thomas Lempert
May 27, 2008·Journal of Neurology·Yoon-Hee ChaRobert W Baloh
Jun 19, 2008·Annual Review of Neuroscience·Kenneth H Britten
Dec 4, 2012·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Yoon-Hee ChaRobert W Baloh
Sep 21, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tatyana A YakushevaDora E Angelaki
May 6, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sun-Young OhSeul-Ki Jeong
Jul 26, 2014·BioMed Research International·Francesco LacquanitiMyrka Zago
Aug 1, 2014·Frontiers in Neurology·Mingjia DaiCatherine Cho
Feb 12, 2015·Therapeutics and Clinical Risk Management·Elizabeth R DuvalIsrael Liberzon
Mar 3, 2015·Annals of the New York Academy of Sciences·Yoon-Hee Cha
Aug 8, 2015·PloS One·Yoon-Hee Cha, Shruthi Chakrapani
Jul 21, 2016·Human Brain Mapping·Katharina FeldkerThomas Straube
Sep 24, 2016·Neuron·Nicolas W SchuckYael Niv
Feb 21, 2018·Frontiers in Neurology·Bernard CohenCatherine Cho
Jun 22, 2018·Annals of Clinical and Translational Neurology·Pauline PoppMarianne Dieterich
May 3, 2019·Journal of Neurology·A SchepermannM Wuehr

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Citations

Mar 3, 2021·Fortschritte der Neurologie-Psychiatrie·Sandra Becker-Bense, Doreen Huppert
Mar 23, 2021·Frontiers in Neurology·Yoon Hee ChaHan Yuan

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Software Mentioned

MdDS
AFNI
ANATICOR
Syngo
Statistical Package for Social Sciences software ( SPSS

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