Neural mechanisms of reward processing associated with depression-related personality traits

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Akina Umemoto, Clay B Holroyd

Abstract

Although impaired reward processing in depression has been well-documented, the exact nature of that deficit remains poorly understood. To investigate the link between depression and the neural mechanisms of reward processing, we examined individual differences in personality. We recorded the electroencephalogram from healthy college students engaged in a probabilistic reinforcement learning task. Participants also completed several personality questionnaires that assessed traits related to reward sensitivity, motivation, and depression. We examined whether behavioral measures of reward learning and event-related potential components related to outcome processing and reward anticipation-namely, the cue and feedback-related reward positivity (RewP) and the stimulus preceding negativity (SPN)-would link these personality traits to depression. Participants who scored high in reward sensitivity produced a relatively larger feedback-RewP. By contrast, participants who scored high in depression learned the contingencies for infrequently rewarded cue-response combinations relatively poorly, exhibited a larger SPN, and produced a smaller feedback-RewP, especially to outcomes following cue-response combinations that were frequently rewa...Continue Reading

Citations

Aug 3, 2018·Psychophysiology·Qi LiYa Zheng
Feb 12, 2020·Cognitive, Affective & Behavioral Neuroscience·Katharina PaulEddie Harmon-Jones
Oct 28, 2019·Frontiers in Behavioral Neuroscience·Belel Ait OumezianeDan Foti
Jun 27, 2020·Behavior Therapy·Elaine M BolandPhilip R Gehrman
Jan 6, 2021·NeuroImage. Clinical·Samantha V AbramSusanna L Fryer
Feb 20, 2018·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·James E GlazerRobin Nusslock
May 18, 2021·Stress : the International Journal on the Biology of Stress·Kreshnik BuraniGreg Hajcak

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