Neural mechanisms of swallowing: neurophysiological and neurochemical studies on brain stem neurons in the solitary tract region

Dysphagia
B J Sessle, J L Henry

Abstract

Neurophysiological studies of the nuclei of the tractus solitarius (NTS) and adjacent regions have provided a partial understanding of the integrative brainstem network underlying swallowing and related functions such as respiration. The NTS is also richly endowed with an abundance of neuropeptides and other neuroactive substances, but only limited information is available on their influences on neurons involved specifically in swallowing. Since dysfunction of these neurophysiological and neurochemical regulatory mechanisms in the NTS region may be important in pathophysiological conditions such as dysphagia, increased awareness of and focus on these mechanisms are warranted. This paper outlines recent neurophysiological and neurochemical data that provide information on the afferent inputs and neurophysiological properties of neurons in NTS and adjacent caudal brainstem regions implicated in swallowing, respiration, and respiratory-related reflexes.

References

Mar 1, 1978·The Journal of Comparative Neurology·A C Cuello, I Kanazawa
Dec 1, 1978·Acta Physiologica Scandinavica·J M LundbergS Said
Jan 1, 1979·Progress in Neurobiology·C H HockmanA Weerasuriya
Apr 1, 1978·The Journal of Physiology·R HardingM E McClelland
Jan 5, 1979·Brain Research·J ChampagnatV Leviel
Aug 1, 1976·Experimental Neurology·D Bieger, C H Hockman
Aug 15, 1986·Neuroscience Letters·N LindeforsU Ungerstedt
Dec 1, 1987·The American Review of Respiratory Disease·R Uddman, F Sundler
May 1, 1989·Advances in Dental Research·A T Storey, D J Kenny
May 3, 1988·Neuroscience Letters·A S FoutzM Denavit-Saubié
Oct 11, 1988·European Journal of Pharmacology·M R DashwoodK M Spyer
Aug 8, 1985·The Journal of Comparative Neurology·S R VincentJ C Brown
Mar 1, 1987·Brain Research Bulletin·M A Hashim, D Bieger
Jul 1, 1986·Journal of Applied Physiology·M RunoldB B Fredholm
Jun 1, 1987·Journal of Applied Physiology·A M Taveira da SilvaR A Gillis

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Citations

Jan 1, 1993·Dysphagia·R E Martin, B J Sessle
Jan 1, 1992·Dysphagia·M C Kagel, N A Leopold
Jan 1, 1992·Dysphagia·S L Hamlet, Y Momiyama
Mar 19, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Martin J McKeownWendy C Gehm
May 29, 2009·Alzheimer Disease and Associated Disorders·Mee Kyung SuhDuk L Na
Nov 8, 1993·The Journal of Comparative Neurology·E P MtuiD A Ruggiero
Dec 27, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kazuo OkuraGilles J Lavigne
Jan 28, 2014·Annals of Rehabilitation Medicine·Won Ihl RheeSae Byuk Ko
May 24, 2003·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G J LavigneB J Sessle
May 15, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·A Sawczuk, K M Mosier
Sep 22, 2017·Scientific Reports·Hiroshi KidaToyojiro Matsuishi
Mar 6, 2002·Journal of Neurophysiology·Ranjinidevi AmbalavanarChristy L Ludlow
Sep 14, 1999·Journal of Neurophysiology·R E MartinB J Sessle
Feb 15, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·M K KernR Shaker
Sep 1, 2018·Journal of Neurology·Hitoshi KawasakiToshimasa Yamamoto

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