PMID: 8942383Sep 1, 1996Paper

Neural network differentiation of optic neuritis and anterior ischaemic optic neuropathy

The British Journal of Ophthalmology
L A LevinS Lessell

Abstract

The efficacy of an artificial intelligence technique, neural network analysis, was examined in differentiating two optic neuropathies with overlapping clinical profiles-idiopathic optic neuritis (ON) and non-arteritic anterior ischaemic optic neuropathy (AION). A neural network was trained with data from 116 patients with 'gold standard' diagnoses of ON or AION. It was then tested with data from 128 patients with presumed ON or AION, and the correlation of the network's diagnosis with that of expert clinicians tabulated. The network agreed with the clinicians on 97.8% (88 of 90) of the patients with presumed ON and 94.7% (36 of 38) of the patients with presumed AION. Youth, female sex, better initial acuity, a central scotoma, subsequent improvement in acuity, or progressive disease biased the network towards a diagnosis of ON, while advanced age, male sex, presence of hypertension, poor initial acuity, an altitudinal field defect, disc oedema, or less improvement in acuity biased the network towards a diagnosis of AION. Neural network analysis is a useful technique for classification of optic neuropathies, particularly where there is overlap of clinical findings.

References

Oct 1, 1992·Neurology·J P Hooge, W K Redekop
Mar 1, 1992·Journal of Radiation Research·J GrahamA Jennings
Dec 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·G ReibneggerH Wachter
Dec 1, 1991·Archives of Ophthalmology·J F Rizzo, S Lessell
Jan 1, 1991·Biological cybernetics·D B Arnold, D A Robinson
Mar 1, 1991·Visual Neuroscience·M Nawrot, R Blake
Jan 1, 1988·Biological cybernetics·H Bourlard, Y Kamp
Dec 1, 1983·Neurology·J NoseworthyG Ebers

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Citations

Aug 10, 2006·Japanese Journal of Ophthalmology·Chun-Pin TsaiAn-Guor Wang
Sep 8, 2004·Ophthalmology·Nathalie J Collignon-RobeJoseph F Rizzo
Nov 10, 2004·Eye·P Riordan-Eva
Jul 3, 2018·Asia-Pacific Journal of Ophthalmology·Leanne Stunkel, Gregory P Van Stavern
Aug 6, 2019·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Fulvio ZaccagnaTarik F Massoud
Mar 4, 1998·Current Opinion in Neurology·E P O'Sullivan, C Kennard

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