Neural signatures of performance feedback in the paced auditory serial addition task (PASAT): an ERP study

BioRxiv : the Preprint Server for Biology
A. SommerChristian Plewnia


Due to its importance for successful human behavior, research into cognitive control functioning has gained increasing interest. The paced auditory serial addition task (PASAT) has been used to test and train this fundamental function. It is a challenging task, requiring a high cognitive load in a stressful and frustrating environment. Its underlying neural mechanisms, however, are still unclear. To explore the neural signatures of the PASAT and their link to ongoing cognitive processing, feedback locked event-related potentials were derived from healthy participants during an adaptive 2-back version of the PASAT. Larger neural activation after negative feedback was found for feedback related negativity (FRN), P300 and late positive potential (LPP). In early stages of feedback processing (FRN), a larger difference between positive and negative feedback responses was associated with poorer overall performance, whereas this association was inverted for the later stages (P300 and LPP). This indicates stage-dependent associations of neural activation after negative information and cognitive functioning. Conceivably, increased early responses to negative feedback signify distraction whereas higher activity at later stages reflect co...Continue Reading

Related Concepts

Cancer Progression
Transcription Initiation
Massively-Parallel Sequencing
Protein S
Cross-Sectional Studies
Cancer Vaccines
Malignant Neoplasms

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Cancer Sequencing

Several sequencing approaches are employed to understand and examine tumor development and progression. These include whole genome as well as RNA sequencing. Here is the latest research on cancer sequencing.

Cancer Genomics (Preprints)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.

Related Papers

Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
Tom N Tombaugh
Multiple Sclerosis : Clinical and Laboratory Research
K S CardinalN L Sicotte
Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
Charles W MathiasRebecca J Houston
© 2020 Meta ULC. All rights reserved