PMID: 12777263Jun 5, 2003Paper

Neural substrates of decision making in adults with attention deficit hyperactivity disorder

The American Journal of Psychiatry
Monique ErnstKaren Bolla

Abstract

The characteristics of attention deficit hyperactivity disorder (ADHD) include abnormalities in reward responsivity that may interfere with decision making. The study examined reward responsivity in ADHD by comparing the neural correlates of decision making in adults with childhood-onset ADHD and in healthy adults. The neural correlates of performance on a decision-making task and a control task were compared in 10 adults with ADHD and 12 age-matched healthy volunteers by using [(15)O]H(2)O positron emission tomography. The decision-making task tested the ability to weigh short-term rewards against long-term losses. The control task matched all components of the decision-making task except for the decision-making process and related contingency. The ventral and dorsolateral prefrontal cortex and the insula were activated during performance of the decision-making task in both the ADHD and healthy groups; however, activation in the ADHD group was less extended and did not involve other regions, such as anterior cingulate and hippocampus, that subserve emotion/memory processes. Direct comparison of data from the ADHD subjects and the healthy volunteers suggested that the healthy subjects engaged the hippocampal and insular regions...Continue Reading

Citations

Jan 11, 2005·Neurotoxicity Research·Anders Fredriksson, Trevor Archer
Sep 1, 2004·Psychopharmacology·Danielle C TurnerBarbara J Sahakian
Aug 4, 2005·Psychopharmacology·Ulrich MüllerTrevor W Robbins
Sep 16, 2006·European Archives of Psychiatry and Clinical Neuroscience·Marc SchneiderMichael Rösler
Feb 24, 2007·Neuropsychology Review·Gerry A Stefanatos, Ida Sue Baron
Feb 6, 2009·Neuropsychology Review·Melissa T Buelow, Julie A Suhr
Jul 2, 2008·The Cerebellum·Patrizia ThomaIrene Daum
Aug 19, 2011·Neurotoxicity Research·Trevor Archer, Richard M Kostrzewa
Mar 30, 2005·Brain Research. Cognitive Brain Research·Diana H FishbeinSteven Grant
Feb 14, 2006·Psychological Medicine·Monique ErnstMichael Hardin
Apr 2, 2005·Journal of the International Neuropsychological Society : JINS·Eileen M MartinAntoine Bechara
May 25, 2007·Journal of the International Neuropsychological Society : JINS·L Malloy-DinizA Bechara
Sep 18, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·George Bush
May 15, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nicholas W SimonBarry Setlow
Mar 14, 2007·Cognitive Neuropsychiatry·Bob BermondPeter P Moormann
Aug 20, 2010·Developmental Neuropsychology·Eva GermanòPaolo Curatolo
May 10, 2012·Social Cognitive and Affective Neuroscience·Sarah M HelfinsteinNathan A Fox
Nov 13, 2008·The Journal of Trauma·Gabriel E RybCarl A Soderstrom
Aug 30, 2008·Journal of Attention Disorders·T Sigi HaleSusan L Smalley
Dec 17, 2009·Journal of Attention Disorders·Nikos MakrisStephen V Faraone
Jul 29, 2008·BMC Neuroscience·Ching-Hung LinJen-Chuen Hsieh
Jun 29, 2005·Behavioral and Brain Functions : BBF·Maggie E ToplakRosemary Tannock
Dec 2, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nicholas W SimonBarry Setlow
May 23, 2014·Journal of Personality Disorders·Jeannette LeGrisPaul S Links
Oct 27, 2006·Journal of Abnormal Child Psychology·Hilde M GeurtsEveline A Crone
May 1, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S A A MassarJ L Kenemans
Sep 28, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Tai-Li ChouSusan Shur-Fen Gau
Dec 12, 2012·Research in Developmental Disabilities·Maria Luz Gonzalez-GadeaAgustin Ibanez
Nov 13, 2012·Psychiatry Research·Melissa Patricia Lopez-LarsonDeborah Yurgelun-Todd
Feb 22, 2012·Medical Hypotheses·Elizabeth E Van VoorheesScott H Kollins
Feb 7, 2012·Journal of Psychiatric Research·Nichole A DuarteUNKNOWN Translational Methamphetamine AIDS Research Center Group
May 21, 2011·Pharmacology, Biochemistry, and Behavior·L Cinnamon BidwellScott H Kollins
Jun 24, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Lorna SchlochtermeierAndreas Ströhle

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