Neurally adjusted ventilatory assist compared to other forms of triggered ventilation for neonatal respiratory support.

The Cochrane Database of Systematic Reviews
Thomas E RossorAnne Greenough

Abstract

Effective synchronisation of infant respiratory effort with mechanical ventilation may allow adequate gas exchange to occur at lower peak airway pressures, potentially reducing barotrauma and volutrauma and development of air leaks and bronchopulmonary dysplasia. During neurally adjusted ventilatory assist ventilation (NAVA), respiratory support is initiated upon detection of an electrical signal from the diaphragm muscle, and pressure is provided in proportion to and synchronous with electrical activity of the diaphragm (EADi). Compared to other modes of triggered ventilation, this may provide advantages in improving synchrony. Primary• To determine whether NAVA, when used as a primary or rescue mode of ventilation, results in reduced rates of bronchopulmonary dysplasia (BPD) or death among term and preterm newborn infants compared to other forms of triggered ventilation• To assess the safety of NAVA by determining whether it leads to greater risk of intraventricular haemorrhage (IVH), periventricular leukomalacia, or air leaks when compared to other forms of triggered ventilation Secondary• To determine whether benefits of NAVA differ by gestational age (term or preterm)• To determine whether outcomes of cross-over trials per...Continue Reading

References

Apr 1, 1986·Early Human Development·A GreenoughJ Pool
Mar 24, 1984·Lancet·A Greenough, C J Morley
Nov 1, 1983·The Journal of Pediatrics·A GreenoughJ Davis
Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·A H Jobe, E Bancalari
Mar 6, 2004·Seminars in Neonatology : SN·Steven M Donn, Sunil K Sinha
Feb 7, 2008·The Cochrane Database of Systematic Reviews·A GreenoughA D Milner
Feb 22, 2011·Respiratory Care·Robert M Kacmarek
Jun 5, 2012·The Journal of Pediatrics·Juyoung LeeJung-Hwan Choi
Oct 27, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·H SteinD B White
Nov 18, 2014·Neonatology·Federico LonghiniPaolo Navalesi
Dec 17, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·Prashanth BhatAnne Greenough
Jan 8, 2017·Pediatrics International : Official Journal of the Japan Pediatric Society·Juyoung LeeYong Hoon Jun
Feb 10, 2017·European Journal of Pediatrics·Sandeep ShettyAnne Greenough

❮ Previous
Next ❯

Citations

Mar 17, 2020·The Cochrane Database of Systematic Reviews·Dimple GoelTim Schindler
Dec 1, 2020·Frontiers in Pediatrics·Wes OnlandAnton H van Kaam
May 1, 2021·Children·Tobias MuehlbacherManuel B Bryant

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Cochrane Database of Systematic Reviews
Anne GreenoughA D Milner
The Cochrane Database of Systematic Reviews
Anne GreenoughAdesh Sundaresan
The Cochrane Database of Systematic Reviews
Anne GreenoughA D Milner
The Cochrane Database of Systematic Reviews
Keith J BarringtonThomas Pennaforte
The Cochrane Database of Systematic Reviews
Claus KlingenbergPeter G Davis
© 2022 Meta ULC. All rights reserved