Neuritic plaque-like structures in the rat cerebellum following prolonged alcohol consumption

Experientia
M M Paula-Barbosa, M A Tavares

Abstract

Primitive neuritic plaques were observed in the inner third of the molecular layer of the cerebellar cortex of rats following chronic alcohol consumption. Neurites were identified as dystrophic parallel fiber boutons. Amyloid material dispersed among neurites was not clearly recognized, dystrophic some fibrils were frequently seen among them. Astrocytic processes were noted in the periphery of the plaque. Microglial reaction, however, was non-existent. The rarity of these lesions in the rat cerebellum and their probable relation to long periods of alcohol consumption is discussed.

References

Apr 1, 1978·Journal of the Neurological Sciences·M M Paula-BarbosaC Cruz
Nov 1, 1974·Journal of Neurocytology·V Chan-PalayS M Billings-Gagliardi
Oct 1, 1973·Journal of Neuropathology and Experimental Neurology·H M WiśniewskiR D Terry
Apr 1, 1968·Journal of Gerontology·J Hollander, C H Barrows
Jul 1, 1967·Journal of Neuropathology and Experimental Neurology·P W Lampert
Jan 1, 1967·Journal of Neuropathology and Experimental Neurology·N K GonatasI Evangelista
Jan 1, 1982·Experimental Brain Research·D M BowenA N Davison
Jan 1, 1983·Alcoholism, Clinical and Experimental Research·M A Tavares, M M Paula-Barbosa
Dec 1, 1982·Experimental Neurology·M A Tavares, M M Paula-Barbosa
Jan 1, 1981·Alcoholism, Clinical and Experimental Research·D W WalkerW C Abraham
Feb 1, 1980·Journal of the Neurological Sciences·M M Paula-BarbosaC Cruz
Jan 1, 1956·Archiv für Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift für die gesamte Neurologie und Psychiatrie·A VON BRAUNMUHL
Jul 1, 1961·The American Journal of Clinical Nutrition·M VICTOR, R D ADAMS
Jan 1, 1964·Journal of Neuropathology and Experimental Neurology·P LAMPERTA PENTSCHEW

❮ Previous
Next ❯

Citations

Jun 1, 1997·Anatomia, histologia, embryologia·S WenischG Hummel
Jun 1, 1987·Alcoholism, Clinical and Experimental Research·M A TavaresA Cadete-Leite
Apr 22, 2009·Journal of Neuroscience Research·Leena AhoIrina Alafuzoff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.