PMID: 8583759Oct 1, 1995Paper

Neuroaxonal dystrophy in a litter of papillon pups

The Journal of Small Animal Practice
R J FranklinI K Ramsey

Abstract

A litter of five 14-week-old papillon puppies was referred for investigation of pelvic limb ataxia. Clinical examination revealed signs of ataxia, hypermetria and depressed postural reflexes affecting all four limbs. The severity of these signs varied between members of the litter. The condition became progressively worse and by 19 weeks of age all but the least severely affected pup (the single male of the litter) had deteriorated to the point that euthanasia was indicated on humane grounds. Pathological examination revealed widespread changes in both white and grey matter of the neuraxis caudal to the forebrain, particularly involving the dorsolateral white matter of the spinal cord, which were characterised by axonal swellings typical of neuroaxonal dystrophy.

References

Nov 9, 1985·The Veterinary Record·W F Blakemore, A C Palmer
May 1, 1967·Acta Neuropathologica·D R CordyG E Bradford
Oct 1, 1969·The Journal of Nutrition·K C HayesJ E Rousseau
May 1, 1983·Journal of Neuropathology and Experimental Neurology·L C CorkJ W Griffin
Jul 1, 1982·New Zealand Veterinary Journal·R G ClarkG Mitchell

❮ Previous
Next ❯

Citations

Jul 21, 2005·New Zealand Veterinary Journal·R D JollyJ J Hopwood
Nov 19, 2011·Journal of Veterinary Internal Medicine·C J FinnoJ E Madigan
Sep 16, 2011·Journal of the American Veterinary Medical Association·Monica AlemanJohn E Madigan
Jun 5, 2007·The Journal of Small Animal Practice·S TamuraK Uchida
Mar 18, 2006·Journal of Comparative Pathology·D M BouleyS J Hayflick
Jun 2, 2020·Toxicologic Pathology·Ingrid D PardoXavier Palazzi
Jun 6, 2017·Veterinary Pathology·Sara Degl'InnocentiCarlo Cantile

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxia telangiectasia (MDS)

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Related Papers

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
K P CarmichaelK Klappenbach
Journal of Neuropathology and Experimental Neurology
L C CorkJ W Griffin
© 2021 Meta ULC. All rights reserved