Neurobehavioral function in children with low blood lead concentrations

Neurotoxicology
Jin-Young MinDomyung Paek

Abstract

Debate continues as to whether low blood lead level, even below 5 microg/dl, impairs neurodevelopmental function in children. This study assessed the association between neurodevelopmental performance and lead exposure below 5 microg/dl in Korean children. Data were collected from 61 children, aged 7-16 years with a mean blood lead level of 2.9 microg/dl, who participated with their mothers. Neurodevelopmental function was measured with computer-based neurobehavioral tests. The analyzed data included children's performances on five neurobehavioral tests as the dependent variables, and children's blood lead level, sex, age, and mother's performance as the four independent variables. For simple reaction time and digit span, which, respectively reflect attention and short-term memory, there was a small and significant association between the children's neurodevelopmental performance and their blood lead levels (p=0.05, 0.08, respectively). Our study suggests that low blood lead below 5 microg/dl can influence children's neurobehavioral performance.

References

Jan 1, 1985·International Archives of Occupational and Environmental Health·J HunterR Lansdown
Jul 1, 1994·Environmental Research·D BellingerM Rabinowitz
Mar 1, 1994·Archives of Environmental Health·D BellingerH L Needleman
Jan 1, 1993·Neurotoxicology and Teratology·K M Stiles, D C Bellinger
Jul 1, 1996·Neurotoxicology and Teratology·A M Williamson
Jan 1, 1996·International Archives of Occupational and Environmental Health·J S YangD H Sohn
Nov 6, 1998·Journal of the Neurological Sciences·S A CounterF Ortega
Dec 13, 2002·Brain : a Journal of Neurology·Theodore I Lidsky, Jay S Schneider
Apr 25, 2003·American Journal of Obstetrics and Gynecology·Eugene EmoryJoseph Chevalier
Aug 2, 2003·The New England Journal of Medicine·David C Bellinger, Herbert L Needleman
Nov 1, 2003·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·H L Needleman, D Bellinger
Apr 29, 2004·Neurotoxicology and Teratology·Lisa M ChiodoJoseph L Jacobson
Jun 17, 2004·Environmental Health Perspectives·Karin KollerLen Levy
Mar 1, 2005·Neurotoxicology and Teratology·Christine DesprésGina Muckle
May 7, 2005·International Journal of Occupational and Environmental Health·David C BellingerKalpana Balakrishnan
Apr 20, 2006·Neurotoxicology·Joon SakongJong-Hak Chung

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Citations

Jun 12, 2008·Environmental Geochemistry and Health·Ray W BrownHoward W Mielke
Mar 31, 2009·Journal of Immigrant and Minority Health·Ray W Brown, Thomas Longoria
Feb 27, 2009·Journal of Environmental Monitoring : JEM·Ali BazziAaron M Linder
Mar 25, 2009·Journal of Toxicology and Environmental Health. Part a·S Allen CounterFernando Ortega
Sep 11, 2010·Environmental Health Perspectives·Paul A EubigSusan L Schantz
May 15, 2013·Neurotoxicology and Teratology·Samuel M PetersonJennifer L Freeman
Oct 5, 2010·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Christina SobinEva de la Riva
Jul 17, 2015·International Journal of Environmental Health Research·Flavia L BarbieriThomas Keil
Jun 26, 2007·International Journal of Hygiene and Environmental Health·Kyoung-Bok MinDomyung Paek
Sep 16, 2014·Journal of Applied Toxicology : JAT·Mayra Gisel Flores-Montoya, Christina Sobin
May 6, 2015·Toxicology Letters·Mayra Gisel Flores-MontoyaChristina Sobin
Sep 18, 2012·Neurotoxicology·Kyeong-Soo LeeJoon Sakong
Apr 1, 2018·Autism Research : Official Journal of the International Society for Autism Research·Jing WuJi-Sheng Han
Mar 21, 2008·Reviews on Environmental Health·Lawrence Hwang
Mar 28, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Malavika LPraveen Sharma
Jul 6, 2021·Journal of the Chinese Medical Association : JCMA·Tai-Jay ChangDe-Ming Yang

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