Neurobehavioural test batteries: current status, critical evaluation and new directions

Toxicology Letters
A M Williamson

Abstract

Neurobehavioural techniques are currently making a contribution to knowledge in toxicology which is being used to set safety limits of exposure to hazards. This, however, puts pressure on researchers in the field to ensure that the methods used are the best and most informative available. A review of the neurobehavioural tests currently in use shows that there are a number of issues that need to be addressed to strengthen and increase their utility. Issues include test selection and the validity, reliability and sensitivity of tests, bias and confounding of measurement in the testing session and problems in interpreting the results.

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