Neurobiology: Crowdsourcing CO2 to Conserve Brain Energy.

Current Biology : CB
Ewan St John Smith, Thomas J Park

Abstract

Naked mole-rats are adapted to living in a low-oxygen and high-CO2 environment. Elevated environmental CO2 inhibits brain activity and has acted as a selection pressure to reduce GABAergic tone, which in turn reduces energetic needs in a hypoxic habitat.

References

Jan 1, 1958·The American Journal of Physiology·D M WOODBURYD A BRODIE
Dec 17, 2011·Science·Ewan St John SmithGary R Lewin
Feb 6, 2017·Proceedings. Biological Sciences·Elizabeth de WolfNicholas Dale
Dec 22, 2017·Biology Letters·Aaron N IlacquaMatthew E Pamenter
May 8, 2018·Neuroscience and Biobehavioral Reviews·Joran T SchulteHilgo Bruining
Jan 8, 2019·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Kenneth C Catania
Jan 30, 2020·Molecular Pain·James Rf HockleyEwan St J Smith
Feb 7, 2020·Physiology·Rochelle BuffensteinHolly M Brown-Borg
May 4, 2020·Current Biology : CB·Michael ZionsDan P McCloskey

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