Neurochemical correlates of muricidal behavior in rats

Neuropsychobiology
L ValzelliA Sala

Abstract

Surgical, pharmacological or environmental manipulation are widely employed to induce muricidal behavior in naive laboratory male rats. The genetic predisposition of an animal strain to kill mice remains, however, an important factor to obtain the muricidal reaction. Data from the pertinent literature suggest that muricidal behavior may possibly be sustained by increased dopaminergic or catecholaminergic activity in the presence of reduced serotoninergic activity. The results here presented indicate, instead, that complete abolition of brain serotoninergic control, i.e., maximal depletion of brain serotonin, is just enough per se to induce muricidal activity. Further, this chemically-induced muricidal activity goes well beyond any pre-existing strain predisposition to kill mice or not.

Citations

Jul 1, 1985·Biological Psychiatry·J A Jesberger, J S Richardson
Jan 1, 1982·Neuroscience and Biobehavioral Reviews·D J Albert, M L Walsh
Jan 1, 1984·Neuroscience and Biobehavioral Reviews·D J Albert, M L Walsh
Sep 1, 1992·Brain Research. Brain Research Reviews·S E MolchanT Sunderland
Jan 1, 1995·Brain Research Bulletin·S MiachonR Cespuglio
Jan 11, 1992·Neuroscience and Biobehavioral Reviews·J S Brown
Oct 10, 2001·Hearing Research·A W HarkriderD McFadden
Jan 24, 1998·Archives of Physiology and Biochemistry·S GiammancoM La Guardia
Mar 1, 1990·Archives internationales de physiologie et de biochimie·S GiammancoM A Paderni
Oct 1, 1981·Pharmacological Research Communications·L ValzelliM Dalessandro
Apr 1, 1983·Pharmacological Research Communications·L ValzelliM Dalessandro
Jan 1, 1984·Progress in Neuro-psychopharmacology & Biological Psychiatry·L Valzelli

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