Neurocognitive impairments in non-deprived smokers--results from a population-based multi-center study on smoking-related behavior

Addiction Biology
M WagnerG Winterer

Abstract

The aim of the present study was to examine neurocognitive function associated with chronic nicotine use. A total of 2163 healthy participants (1002 smokers, 1161 never-smoking controls) participated in a population-based case-control design. The main outcome measures were six cognitive domain factors derived from a neuropsychological test battery. In smokers, the battery was administered after controlled smoking of one cigarette. Analyses included age, sex and education as covariates. Results demonstrated small, but significant deficits in smokers for visual attention (P<0.001) and cognitive impulsivity (P<0.006), while verbal episodic memory, verbal fluency, verbal working memory, and Stroop-interference did not differ between groups. These attention/impulsivity deficits were also present in smokers with only a low amount of cigarette consumption. Lifetime nicotine use (pack-years) was not correlated with cognition in smokers. In conclusion, this study confirmed subtle and specific cognitive deficits in non-deprived smokers. The independence of these deficits from consumption intensity may argue for an a priori deficit of some cognitive abilities in smokers. These specific deficits may constitute intermediate phenotypes for g...Continue Reading

References

May 1, 1979·The Journal of Nervous and Mental Disease·M Selz, R M Reitan
Sep 1, 1991·British Journal of Addiction·T F HeathertonK O Fagerström
Jun 1, 1989·Drug and Alcohol Dependence·F R SnyderJ E Henningfield
Feb 1, 1997·Archives of General Psychiatry·J M GoldD R Weinberger
Apr 15, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·J A CervillaA Mann
Nov 7, 2002·American Journal of Epidemiology·Sandra KalmijnLenore J Launer
May 30, 2003·American Journal of Public Health·Marcus RichardsMichael E J Wadsworth
Sep 6, 2003·Age and Ageing·Robert D HillLars Bäckman
Mar 17, 2004·Current Opinion in Pharmacology·Paul A NewhouseAbhay Singh
Apr 7, 2005·Behavioral and Cognitive Neuroscience Reviews·Suzanne H Mitchell
Jun 6, 2006·Psychopharmacology·Peter S HendricksThomas H Brandon
Dec 5, 2006·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Avi YakirBernard Lerer
Jun 19, 2007·American Journal of Epidemiology·Kaarin J AnsteyRichard O'Kearney
Jul 7, 2007·Human Molecular Genetics·Georg WintererJürgen Gallinat
Aug 11, 2007·Neuropsychology Review·Gary E Swan, Christina N Lessov-Schlaggar
Jun 4, 2008·The American Journal of Psychiatry·Laura Jean BierutAlison M Goate
Jun 11, 2008·Archives of Internal Medicine·Séverine SabiaArchana Singh-Manoux
Feb 16, 2010·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Lisa S KahalleyPamela S Hinds
Apr 16, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nadine PetrovskyVeena Kumari
Apr 24, 2010·Psychopharmacology·Stephen J HeishmanEdward G Singleton
Jun 12, 2010·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·A MobascherG Winterer
Oct 5, 2010·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Georg WintererDan Rujescu
Dec 9, 2010·International Journal of Environmental Research and Public Health·Timothy C DurazzoSara Jo Nixon
Mar 12, 2011·Addiction Biology·Jürgen BrinkmeyerGeorg Winterer

❮ Previous
Next ❯

Citations

Feb 2, 2016·Journal of Dual Diagnosis·Mehmet SofuogluKathleen M Carroll
Aug 13, 2015·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·H ChoS W Seo
Nov 29, 2015·Psychiatry Research·Christian NúñezGildas Brébion
Sep 15, 2015·Alcoholism, Clinical and Experimental Research·Andrea H WeinbergerRenee D Goodwin
May 23, 2015·Addiction Biology·Rick E Bernardi
Jul 20, 2014·Drug and Alcohol Dependence·Timothy C DurazzoUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Jun 25, 2015·Frontiers in Aging Neuroscience·Ganna AndrosovaReinhard Schneider
Nov 2, 2014·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Prescott T LeachThomas J Gould
Oct 14, 2014·Current Psychiatry Reports·Kathleen A Garrison, Marc N Potenza
Mar 18, 2017·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Linda ChangDaniel Alicata
Mar 10, 2016·PloS One·Valentin FlaudiasSébastien Guillaume
Nov 9, 2018·Alcoholism, Clinical and Experimental Research·Andrea H WeinbergerRenee D Goodwin
May 17, 2019·Substance Use & Misuse·Megan M KangiserKrista M Lisdahl
Jun 14, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Timothy C DurazzoUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Nov 17, 2019·The European Journal of Neuroscience·Sarah E DonohueMircea A Schoenfeld
Jul 21, 2016·Brain Imaging and Behavior·Yangding LiJie Tian
Oct 12, 2017·Frontiers in Psychology·Samantha J BrooksHelgi B Schiöth
May 4, 2021·Journal of Alzheimer's Disease : JAD·Taylor J KrivanekKirk R Daffner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the International Neuropsychological Society : JINS
John A SchinkaPatricia Isbell Ordorica
Archives of Gerontology and Geriatrics
Cheng-Ching WangChi-Hua Yen
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Carol S MyersStephen J Heishman
© 2022 Meta ULC. All rights reserved