Neurocognitive improvements following endovascular repair of vein of Galen malformation in a child

Journal of Neurosurgery. Pediatrics
Robyn A HowarthAlejandro Berenstein

Abstract

Cognitive regression is a well-described presentation of vein of Galen aneurysmal malformations (VGAMs) in childhood. However, it remains unclear whether successful treatment of the malformation can reverse cognitive regression. Here, the authors present the case of a 5-year-old girl with a VGAM that was treated with staged endovascular embolization procedures. Comprehensive neurocognitive assessments were completed before intervention and approximately 6 years after initial presentation. There were significant age-matched improvements in this child's neurocognitive profile over this period. The authors believe that timely and successful treatment of VGAM in children may not only stabilize the associated cognitive deterioration but, in some cases, may ameliorate these deficits. Details of this case and a discussion of neurocognitive deficits related to VGAM are presented.

References

May 1, 1986·Journal of Neurosurgery·J P Mickle, R G Quisling
Mar 1, 1974·Journal of Neurosurgery·D M LongL A French
Mar 1, 1994·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G RodeschP Lasjaunias
Jun 1, 1996·Archives of Physical Medicine and Rehabilitation·K N WongT E Strax
Oct 8, 1997·Neurosurgery·A BerensteinR Verma
Aug 29, 1998·Journal of Child Neurology·R NassA Berenstein
Oct 5, 2001·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·R NassA Berenstein
Jul 15, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·Philippe GailloudChristoph U Lehmann
Oct 21, 2006·Neurosurgery·Pierre L LasjauniasRicardo Garcia-Monaco
Jul 25, 2007·Neuroimaging Clinics of North America·H AlvarezPierre Lasjaunias
Nov 3, 2009·Neurosurgical Focus·Stanley HoangRaphael Guzman
Jun 29, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Alejandro BerensteinWalter Molofsky
Jul 8, 2010·Archives of Disease in Childhood·N McSweeneyV Ganesan
Nov 3, 2010·Journal of Neurosurgery. Pediatrics·Dhruv KhullarKetan R Bulsara
Apr 3, 2012·World Journal of Radiology·Jason A EllisPhilip M Meyers

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Citations

Jan 20, 2018·Journal of Neurosurgery. Pediatrics·Daniel DuranKristopher T Kahle
May 28, 2019·Archives of Disease in Childhood·Stephanie MalarbiRod W Hunt
Nov 26, 2016·BioMed Research International·Hong-Yun Li, Ying-Hui Hua

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