Neurocognitive markers of suicide vulnerability in the elderly: a review

Gériatrie et psychologie neuropsychiatrie du vieillissement
S Richard-DevantoyGeneviève Letourneau

Abstract

a comprehensive literature review suggests that suicidal behaviour results from a complex interplay between stressful events and vulnerability factors including cognitive deficits. The aim of this systematic literature review was to identify the neurocognitive markers associated with suicide vulnerability in elderly people. a systematic English Medline literature search of cohort studies, case-control studies and cross-sectional studies published between January 1960 and December 2012 was performed, combining the MeSH terms "Suicide", "Neuropsychology", "Neuropsychological Tests", "Executive Function", "Magnetic Resonance Imaging", "Diffusion Magnetic Resonance Imaging", "Positron-Emission Tomography", "Prefrontal Cortex", "Tomography, Emission-Computed, Single-Photon", and "Diffusion Tensor Imaging". The abstract selection was based on the Strobe checklist for observational studies. of the 446 original articles, 10 neuropsychological and 4 brain imaging studies were selected. The number of suicidal subjects ranged from 10 to 29 (mean age=66.8 to 79.1 years old, 0-85% women). Executive functions, in particular decision-making and cognitive inhibition, were more impaired in the depressed elderly with a history of suicide attempt...Continue Reading

Citations

Aug 13, 2014·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Stephane Richard-DevantoyFabrice Jollant
Jun 11, 2015·Ciência & saúde coletiva·Maria Cecília de Souza Minayo, Fátima Gonçalves Cavalcante
Oct 13, 2020·Frontiers in Psychology·Gabrielle Michaud-DumontCharles Viau-Quesnel

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