Abstract
This review is a survey of the recent literature investigating the etiology and the relative incidence of postoperative neurological and cognitive dysfunction after cardiac surgery. Several studies reviewed here have employed transcranial Doppler for detection of cerebral emboli and compared results between patients undergoing beating-heart versus conventional cardiopulmonary bypass. A transcranial Doppler device ostensibly discriminating between particulate and gaseous emboli has additionally been employed, yet despite a consistently lower incidence of cerebral emboli associated with avoidance of cardiopulmonary bypass, several groups have reported similar incidences of cognitive dysfunction across these procedures, suggesting other, potentially more important, factors. Two recent studies have focused on the hazards associated with perioperative anemia in both infants and older patients, and which can result in developmental delay or profound changes in cerebral blood flow. A further study has identified an adverse interaction with postoperative hypoxia. The use of intraortic filtration for capture and removal of particulate macroemboli has been associated with a reduction in the incidence of clinically apparent central-nervou...Continue Reading
References
Sep 10, 2003·The Annals of Thoracic Surgery·Christian LundDavid Russell
Oct 8, 2003·The Annals of Thoracic Surgery·Charles W HogueKenneth E Freedland
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·S M BrowneD P Taggart
Nov 25, 2003·Journal of the International Neuropsychological Society : JINS·Katherine P RankinJ Galen Buckwalter
Nov 25, 2003·Zeitschrift für Kardiologie·P EmmrichF W Mohr
Dec 4, 2003·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Jan StygallMichael J Harrison
Dec 12, 2003·The Annals of Thoracic Surgery·Thomas F FloydJohn A Detre
Dec 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Richard A JonasJane W Newburger
Dec 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Christoph SchmitzArmin Welz
Jan 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·Jan BuceriusFriedrich W Mohr
Feb 5, 2004·The Annals of Thoracic Surgery·P Michael HoKarl E Hammermeister
Mar 17, 2004·Heart·D van DijkUNKNOWN Octopus Study Group
Apr 6, 2004·British Journal of Anaesthesia·B S SilbertP S Myles
Apr 27, 2004·Surgery Today·Yuji KadoiFumio Goto
Jun 3, 2004·The Journal of Thoracic and Cardiovascular Surgery·Yasir Abu-OmarDavid P Taggart
Jun 24, 2004·Journal of the American Geriatrics Society·Wolf-Peter SchmidtKlaus Berger
Jul 28, 2004·The Annals of Thoracic Surgery·Daniel ZimpferMichael Grimm
Citations
Dec 14, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Ralph J PetrucciMark S Slaughter
May 17, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Adam J WoodsMark Mennemeier
Jun 28, 2011·Journal of Vascular Surgery·Brajesh K LalPeter J Pappas
May 9, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Zeljko ColakVisnja Majeric-Kogler
Feb 6, 2007·Vascular and Endovascular Surgery·Brajesh K Lal
Jul 27, 2010·Seminars in Cardiothoracic and Vascular Anesthesia·John M Murkin
Dec 18, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ryan L HoilandPhilip N Ainslie