Neurocognitive, social and clinical correlates of two domains of hopelessness in schizophrenia

Schizophrenia Research
Paul H LysakerNicole L Hunter

Abstract

While hopelessness has been widely observed in schizophrenia and its clinical significance accepted, research has been equivocal regarding its relationship to symptoms and neurocognition. One possible reason for this is that different domains of hope have differential relationships to outcome. To explore this possibility, two aspects of hope, expectations of the future and motivation to persist were assessed along with neurocognition, personality, symptoms and social function among 52 persons in a post acute phase of schizophrenia. Multiple regressions revealed that neuroticism, verbal memory and income were each uniquely related to expectations of the future, accounting for almost one half of the variance (F=14.3, p<0.0001). By contrast, neuroticism and social isolation were uniquely related to motivational hope (F=13.6, p<0.0001), accounting for 35% of the variance. Positive and negative symptoms were unrelated to either form of hopelessness. Implications for research, and the development of interventions are discussed.

References

Feb 1, 1992·Psychological Reports·J R Hays, K E Buckle
Jan 1, 1990·Schizophrenia Bulletin·S R Kay, S Sevy
Jan 1, 1985·Comprehensive Psychiatry·R E DrakeP G Cotton
Dec 1, 1974·Journal of Consulting and Clinical Psychology·A T BeckL Trexler
Jan 1, 1984·Schizophrenia Bulletin·D W HeinrichsW T Carpenter
Jun 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·L Cipolotti, E K Warrington
Nov 1, 1994·The Journal of Nervous and Mental Disease·J P LindenmayerS Grochowski
Jan 1, 1994·Comprehensive Psychiatry·R M Norman, A K Malla
Oct 6, 1997·The Journal of Nervous and Mental Disease·M KentrosC Capalbo
Jul 7, 1999·Journal of Clinical Psychology·P R Magaletta, J M Oliver
Jul 30, 1999·The Journal of Nervous and Mental Disease·T LecomteN Ricard
Feb 9, 2000·The Journal of Nervous and Mental Disease·R J GurreraB F O'Donnell
Apr 6, 2000·Journal of Health and Social Behavior·E R WrightT J Owens
Aug 16, 2001·The Journal of Nervous and Mental Disease·P H LysakerK A Marks
Aug 22, 2001·Psychological Medicine·J Van Os, P B Jones
Nov 5, 2002·Schizophrenia Research·Paul H LysakerMorris D Bell
Dec 31, 2002·Schizophrenia Research·Chan-Hyung KimHerbert Y Meltzer
Feb 15, 2003·The Journal of Nervous and Mental Disease·Paul H LysakerCatherine A Clements
Aug 12, 2003·Social Psychiatry and Psychiatric Epidemiology·K M HaatainenH Viinamäki

❮ Previous
Next ❯

Citations

Nov 2, 2011·The Psychiatric Quarterly·Yu-Chen KaoChien-Wen Lu
Aug 31, 2010·American Journal of Psychiatric Rehabilitation·Philip T YanosPaul H Lysaker
Nov 8, 2006·Journal of Psychiatric and Mental Health Nursing·J KylmäM Isohanni
Aug 6, 2013·Issues in Mental Health Nursing·Rikard Erik WärdigSally Hultsjö
Jun 23, 2010·International Journal of Psychiatry in Medicine·Onur HamzaogluFeray Gokdogan
Aug 16, 2016·Psychiatry Research·Kelsey A BonfilsMichelle P Salyers
Sep 5, 2017·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Laura HayesCarol Harvey
Dec 20, 2007·The Journal of Nervous and Mental Disease·Ross G WhiteCiaran Mulholland
Sep 17, 2010·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Katerine OsatukeSomaia Mohamed
Mar 14, 2009·The Journal of Nervous and Mental Disease·Kathleen RestifoPatrick E Shrout

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.