Neurocysticercosis

Handbook of Clinical Neurology
O H Del Brutto

Abstract

Known as a disease of swine in ancient civilizations, cysticercosis is currently considered the most common helminthic infection of the nervous system, and a leading cause of acquired epilepsy worldwide. The disease occurs when humans become intermediate hosts of the tapeworm Taenia solium by ingesting its eggs from contaminated food or, most often, directly from a Taenia carrier by the fecal-oral route. Once in the human intestine, Taenia eggs evolve to oncospheres that, in turn, cross the intestinal wall and lodge in human tissues - especially the nervous system - where cysticerci develop. The brain is a hostile environment in which parasites attempt to escape the immune surveillance while the host is trying to drive out the infection. In some cases, cysticerci are destroyed by this immunological attack, while in others, parasites may live unchanged for years. Cysticerci may be located in brain parenchyma, subarachnoid space, ventricular system, or spinal cord, causing a myriad of pathologic changes that are the main changes responsible for the clinical pleomorphism of neurocysticercosis. Seizures are the most common clinical manifestation of the disease, but some patients present with focal deficits, intracranial hypertensio...Continue Reading

Citations

Dec 23, 2015·Expert Review of Neurotherapeutics·Francisco Javier Carod Artal
May 21, 2017·Biomédica : revista del Instituto Nacional de Salud·Carlos Hugo ZapataCarlos Santiago Uribe
Apr 22, 2015·Bulletin de la Société de pathologie exotique·A Mouhari-ToureP Pitche
Aug 9, 2016·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Jesus Ramirez-BermudezTeresa Corona
Jun 14, 2018·Arquivos de neuro-psiquiatria·Anália Cirqueira MilhomemRuy de Souza Lino Júnior
Apr 28, 2019·Clinical Pediatrics·Vidal A VillelaRussell Steele
Oct 30, 2016·Transactions of the Royal Society of Tropical Medicine and Hygiene·Kate BrizziUNKNOWN Bhutan Epilepsy Project
Dec 1, 2017·PLoS Neglected Tropical Diseases·Siddhartha MahantyUNKNOWN Cysticercosis Working Group in Peru
Feb 2, 2021·Continuum : Lifelong Learning in Neurology·Michel Toledano
Jan 15, 2021·Journal of the Neurological Sciences·J ReisA Buguet
May 1, 2021·Radiologic Clinics of North America·Joseph H DonahueSugoto Mukherjee
May 28, 2021·Frontiers in Veterinary Science·Caitlin ButalaSusan Christina Welburn
Jun 24, 2021·Revista Do Instituto De Medicina Tropical De São Paulo·Diana Maritza Parra-CárdenasDiego Fernando Severiche-Bueno
Jul 3, 2021·Asian Journal of Neurosurgery·Sasa ShakyaBasant Pant

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