Neurodevelopment in full-term small for gestational age infants: A nationwide Japanese population-based study

Brain & Development
Akihito TakeuchiHiroyuki Doi

Abstract

To investigate neurological development in small for gestational age (SGA) infants, with a focus on full-term SGA infants. We analyzed data from a large, Japanese, nationwide, population-based longitudinal survey started in 2001. We restricted the study to participants born before 42weeks of gestation (n=46,563). Parents were asked questions about motor and language development when the children were 2.5years old, and about behavioral development at 5.5years. We analyzed the relationships between SGA status and development by logistic regression. Odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated for each outcome for full-term and preterm births, adjusting for potential infant- and parent-related confounding factors. We also calculated the population-attributable fractions to estimate the public impact of SGA births. SGA full-term children were more likely to demonstrate developmental delays at 2.5years, e.g., being unable to walk alone (OR 3.0, 95% CI: 1.7, 5.3), compose a two-phrase sentence (OR 1.5, 95% CI: 1.2, 1.8), or use a spoon to eat (OR 1.5, 95% CI: 1.1, 1.9). SGA status also had some degree of negative impacts on behavioral problems at 5.5years among term children, e.g., being unable to listen wi...Continue Reading

References

Oct 20, 2001·Early Human Development·K SommerfeltL S Bakketeig
May 10, 2002·Journal of the American College of Nutrition·Betty Ruth Carruth, Jean D Skinner
Jul 19, 2005·Brain & Development·Tatsuya OginoYoko Ohtsuka
Jun 10, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·Ester Maria Lundgren, Torsten Tuvemo
Jan 19, 2010·American Journal of Epidemiology·Seungmi YangMichael S Kramer
Mar 9, 2011·Pediatrics·Isabelle GuellecUNKNOWN EPIPAGE Study Group
Jan 3, 2012·Early Human Development·Christine M CornforthEdwin A Mitchell
Feb 4, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T ArcangeliA Bhide
Oct 4, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Stefania LongoM Stronati
Jan 11, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S SavchevF Figueras
Aug 24, 2013·The Journal of Pediatrics·Tsuguhiko KatoIchiro Kawachi
Feb 18, 2014·The Journal of Pediatrics·Takashi YorifujiHiroyuki Doi

❮ Previous
Next ❯

Citations

Nov 29, 2016·Environment International·Takashi YorifujiHiroyuki Doi
Jul 31, 2018·Expert Review of Endocrinology & Metabolism·Lorenzo IughettiFabrizio Ferrari
Jan 19, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Laura LucaccioniFabrizio Ferrari
Sep 25, 2019·American Journal of Obstetrics and Gynecology·Chenxi CaiMargie H Davenport
Aug 13, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Michael T FavaraZubair H Aghai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.