Neurodevelopmental and audiological outcome of healthy term newborns with moderately severe non-haemolytic hyperbilirubinemia

Journal of Paediatrics and Child Health
Ruth Heimler, Ponthenkandath Sasidharan

Abstract

Our objective was to examine the outcome of term infants who developed moderate non-haemolytic jaundice as information regarding the neurodevelopmental outcome of term infants with moderately severe non-haemolytic hyperbilirubinemia remains controversial. Thirty-nine term infants rehospitalised with non-haemolytic hyperbilirubinemia (serum bilirubin levels: 20-30 mg/dL) during the first 2 weeks of life (study group), were assessed and compared to 36 children born at term who did not develop neonatal jaundice (control group). Assessment consisted of the Bailey 2 test, speech evaluation, behavioural hearing test and a neurological examination. The subjects were assessed at a mean age of 3 years. There was no difference between the groups with regard to background data, except for the mean gestational age (38 + 1.3 weeks (study group) vs. 39.5 + 1.4 weeks (control group), P= 0.01). There were no significant differences between the groups in outcome parameters initially, and after correcting for possible confounding factors. None of the children in either of the groups had a neurosensory hearing deficit or any significant neurological deficiency. There was no correlation of outcome parameters with the admission serum Bilirubin leve...Continue Reading

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Citations

Feb 15, 2013·Pediatric Research·Roelineke J LunsingMijna Hadders-Algra
Apr 17, 2013·Brain & Development·Ze D Jiang, Andrew R Wilkinson
May 7, 2013·International Journal of Pediatric Otorhinolaryngology·Olubunmi Victoria AkinpeluSam J Daniel
Jan 13, 2015·Seminars in Fetal & Neonatal Medicine·Vinod K Bhutani, Lois Johnson-Hamerman
Jan 15, 2015·Seminars in Fetal & Neonatal Medicine·Courtney J Wusthoff, Irene M Loe

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