PMID: 7540105Jun 15, 1995Paper

Neurodevelopmental outcome after neonatal extracorporeal membrane oxygenation

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
C M RobertsonM G Grace

Abstract

To determine the neurodevelopmental outcome of neonates who underwent extracorporeal membrane oxygenation (ECMO group) and similarly critically ill newborns with a lower Oxygenation Index who underwent conventional treatment (comparison group), and to determine whether factors such as the underlying diagnosis and the distance transported from outlying areas affect outcome. Multicentre prospective longitudinal comparative outcome study. An ECMO centre providing services to all of western Canada and four tertiary care neonatal follow-up clinics. All neonates who received treatment between February 1989 and January 1992 at the Western Canadian Regional ECMO Center and who were alive at 2 years of age; 38 (95%) of the 40 surviving ECMO-treated subjects and 26 (87%) of the 30 surviving comparison subjects were available for follow-up. ECMO or conventional therapy for respiratory failure. Neurodevelopmental disability (one or more of cerebral palsy, visual or hearing loss, seizures, severe cognitive disability), and mental and performance developmental indexes of the Bayley Scales of Infant Development. Six (16%) of the ECMO-treated children had neurodevelopmental disabilities at 2 years of age, as compared with 1 (4%) of the compari...Continue Reading

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