Neuroencorine Tumor Arising within a Tailgut Cyst in an Adolescent Boy

Fetal and Pediatric Pathology
Tutku SoyerFeridun C Tanyel

Abstract

Neuroendocrine tumors (NET) within tailgut cysts (TC) are usually seen in middle-aged females. A 14 year-old boy who underwent surgical excision of NET within TC is presented to discuss the clinical features, diagnosis and treatment options. A 14-year-old boy with rectal bleeding and constipation had a 5 × 4 cm mass detected upon rectal examination. The cystic mass was totally excised. The histopathological evaluation revealed a low-grade NET within mucularis layer of the cyst showing a positive immunhistochemical staining for cytokeratin and synaptophysin. Although, the malignant transition of TC is commonly observed in middle age females, males and children can also be affected. This is first report of a pediatric TC with malignant transformation. Total surgical excision of cysts is mandatory for local control of the disease and chemotherapy should be reserved for the patients who have positive surgical margins.

References

Feb 1, 1988·American Journal of Clinical Pathology·B M Hjermstad, E B Helwig
Jun 24, 2004·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·B AntaoI D Sugarman
Feb 20, 2010·The British Journal of Surgery·K L MathisR M Devine
Jan 18, 2014·Scottish Medical Journal·J H KimT H Lee
Dec 6, 2014·Case Reports in Surgery·A A AbukarM A Thaha
Apr 11, 2015·Pediatric Surgery International·Nadeem HaiderMark D Stringer

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Citations

Apr 2, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K NicollC Carden

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