Neuroendocrine predictors of emotional and behavioral adjustment in boys: longitudinal follow-up of a community sample.

Psychoneuroendocrinology
Audrey R TyrkaJeanne Brooks-Gunn

Abstract

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been observed in adults and children with mood and anxiety disorders and is thought to be involved in the pathogenesis of these disorders. We recently studied a diverse community sample of boys and found associations of behavioral problems, including symptoms of depression and anxiety, with basal and stress-induced cortisol concentrations. Here we examine cortisol-emotional/behavioral associations at a two-year follow-up and test whether initial cortisol is predictive of worsening emotional/behavioral problems two years later. Seventy-eight 10-14-year-old boys and their mothers completed a battery of psychosocial assessments, provided morning and afternoon saliva samples, and participated in a home visit involving mildly stressful tasks and saliva collection for cortisol assay during a two-year follow-up assessment. Consistent with the findings from our time 1 assessment, greater declines in cortisol across the home-visit challenge task were significantly associated with internalizing and externalizing behaviors as well as attention problems and social problems at the two-year follow-up. In addition, morning and afternoon cortisol concentrations at the initial a...Continue Reading

References

Nov 1, 1974·American Journal of Optometry and Physiological Optics·S Wechsler
Dec 5, 2000·The British Journal of Psychiatry : the Journal of Mental Science·I M GoodyerP M Altham
Feb 24, 2001·Journal of the American Academy of Child and Adolescent Psychiatry·M E WadsworthT M Achenbach
Jul 26, 2006·Journal of Affective Disorders·Sarah L HalliganPeter J Cooper
Mar 28, 2008·Journal of Neuroendocrinology·P Pervanidou
Feb 4, 2011·Clinical Child and Family Psychology Review·John D Guerry, Paul D Hastings

❮ Previous
Next ❯

Citations

Jan 18, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Dafne M SilbermanMaría A Zorrilla Zubilete
Jun 4, 2014·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Brandon A KohrtCarol M Worthman
Dec 3, 2014·Psychoneuroendocrinology·Mihai CărnuţăAndrei C Miu
Oct 26, 2016·Development and Psychopathology·Audrey R TyrkaStephanie H Parade
Oct 25, 2017·International Journal of Environmental Research and Public Health·Regina GrazulevicieneBirute Balseviciene
Mar 8, 2018·International Journal of Environmental Research and Public Health·Inga PetravicieneMark J Nieuwenhuijsen
Sep 5, 2017·Journal of Emotional and Behavioral Disorders·D Anne WiniarskiElizabeth A Whitmore
Jul 30, 2016·Stress : the International Journal on the Biology of Stress·Heidemarie LaurentLaura R Stroud

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.