Neuroendocrine Tumors of the Pancreas

Current Treatment Options in Gastroenterology
James M. McLoughlinJeffrey T. Lamont

Abstract

Neuroendocrine tumors (NETs) are rare tumors of the endocrine pancreas that require a high degree of suspicion for timely diagnosis. Diagnosis is often delayed due to the nonspecific and intermittent presentation of symptoms. As many as 45% to 55% of tumors are nonfunctional and are typically diagnosed secondary to mass effect related symptoms or found incidentally. Functional tumors often are symptom specific and are diagnosed at an earlier stage than nonfunctional tumors. The challenging aspects of treating NETs are localizing the tumors, treating extensive or metastatic disease, and palliating symptoms. Most NETs have an indolent course, and aggressive multimodality treatment is often indicated and encouraged.

References

Aug 1, 1991·The Journal of Clinical Endocrinology and Metabolism·B SkogseidK Oberg
Sep 1, 1994·Annals of Surgery·D L FrakerR T Jensen
Jan 25, 1996·The New England Journal of Medicine·S W LambertsL J Hofland
Jan 1, 1996·Annual Review of Medicine·R R Perry, A I Vinik
Jun 1, 1996·The British Journal of Dermatology·A P BewleyR C Staughton
Jan 14, 1998·Surgery·A E SipersteinA Gitomirsky
May 23, 1998·World Journal of Surgery·G M DohertyJ A Norton
Jun 20, 1998·World Journal of Surgery·D SimonH D Roeher
Aug 12, 1998·Revista da Associação Médica Brasileira·M C MachadoH W Pinotti
Aug 26, 1999·The New England Journal of Medicine·J A NortonR T Jensen
Aug 28, 1999·Lancet·G I UwaifoD L Whitaker-Worth
Nov 5, 1999·Journal of the American College of Surgeons·P H Jordan
Sep 28, 2000·The American Journal of Gastroenterology·M A AndersonJ M Scheiman
Oct 19, 2000·World Journal of Surgery·J F ChatalI Resche
Jul 19, 2001·The Surgical Clinics of North America·K Azimuddin, R S Chamberlain
Jul 19, 2001·The Surgical Clinics of North America·R Brentjens, L Saltz
Jan 5, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K Oberg
May 23, 2002·World Journal of Surgery·Per HellmanAnders Elvin
Jun 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Steven N HochwaldDavid S Klimstra
Sep 3, 2002·World Journal of Surgery·Juan M SarmientoDavid M Nagorney
Aug 30, 2003·Surgical Oncology·Gerard M Doherty
Nov 26, 2003·The American Journal of Gastroenterology·Lucio GulloPaola Tomassetti

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Citations

Jan 27, 2006·World Journal of Gastroenterology : WJG·Wojciech C BlonskiDavid C Metz
Jan 18, 2011·Proceedings·S Michelle ShillerGranger R Scruggs

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