Neuroendoscopic and microscopic transsphenoidal approach for resection of nonfunctional pituitary adenomas

World Journal of Clinical Cases
Zhi-Quan DingQing-Hua Wang

Abstract

Nonfunctional pituitary adenoma is a common type of pituitary adenoma, which can lead to headache, visual field disturbance, and cranial nerve damage due to increased tumor volume. Neuroendoscopic and microscopic transsphenoidal approaches have been widely used in the resection of nonfunctional pituitary adenomas. However, the clinical efficacy in neuroendoscopic and microscopic surgery is still controversial. To explore the clinical efficacy of neuroendoscopic and microscopic transsphenoidal approach for resection of nonfunctional pituitary adenomas. We retrospectively analyzed 251 patients with nonfunctional pituitary adenomas; 138 underwent neuroendoscopic surgery via transsphenoidal approach, and 113 underwent microscopic surgery via transsphenoidal approach between July 2010 and September 2015. All patients were followed up for > 6 mo. Gender, age, course of disease, tumor diameter, tumor location, and percentage of patients with headache, visual impairment, sexual dysfunction, and menstrual disorders were contrasted between the two groups to compare the difference of preoperative data. Cure rate, symptom improvement rate, recurrence rate, the postoperative hospital stay, operating time, intraoperative blood loss, and the ...Continue Reading

References

Nov 4, 2006·Pituitary·Craig A Jaffe
May 11, 2010·Acta neurochirurgica·Neil L Dorward
Dec 3, 2010·The Journal of Allergy and Clinical Immunology·Linda CoxDana Wallace
Dec 18, 2012·Journal of Neurosurgery·Nancy McLaughlinDaniel F Kelly
Jan 8, 2013·Journal of Neurosurgery·Maria KoutourousiouCarl H Snyderman
Jun 28, 2015·Annales d'endocrinologie·Christine Cortet-RudelliPhilippe Chanson
Feb 9, 2018·British Journal of Neurosurgery·Hamideh AkbariAmeneh Ebrahim Valojerdi

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