PMID: 11758794Jan 5, 2002

Neurogenic erectile dysfunction

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
T F Lue


Penile erection is a neurovascular event modulated by psyche and hormones. Erectile dysfunction (ED) has been classified as psychogenic, arteriogenic, neurogenic, endocrinologic, and cavernosal, based on the organs that are involved in penile erection. Among these types, neurogenic ED may be the most common, probably because a deficiency of neurotransmitters is the final common pathway in many diseases and conditions. This review discusses the physiology, pathophysiology, diagnosis, and treatment of erectile function and dysfunction, as well as strategies for future research.


Jan 1, 1992·European Neurology·C SingerJ Sanchez-Ramos
Oct 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·C SingerM Ackerman
Jul 31, 1990·Biochemical and Biophysical Research Communications·L J IgnarroJ Rajfer
Aug 1, 1990·The Journal of Urology·R BlancoR A Cohen
Aug 1, 1990·Archives of Sexual Behavior·A M ZeissJ R Tinklenberg
Oct 1, 1989·The Journal of Urology·I Saenz de TejadaI Goldstein
Apr 20, 1989·The New England Journal of Medicine·I Saenz de TejadaR A Cohen
Feb 1, 1988·Archives of Neurology·A G Herzog
Apr 19, 1971·JAMA : the Journal of the American Medical Association·R D Amelar, L Dubin
Apr 11, 1966·JAMA : the Journal of the American Medical Association·A L Finkle, D V Prian
May 1, 1982·Psychosomatics·J M Ellison
Sep 1, 1982·The Journal of Urology·P C Walsh, P J Donker
Jan 1, 1995·Physiological Reviews·K E Andersson, G Wagner
Mar 1, 1994·Archives of Physical Medicine and Rehabilitation·R Chao, D E Clowers
Aug 1, 1996·Archives of Physical Medicine and Rehabilitation·J DenilC Smythe
Jun 1, 1996·Endocrinology and Metabolism Clinics of North America·L S Hakim, I Goldstein
Feb 1, 1997·International Journal of Radiation Oncology, Biology, Physics·C A MantzS Vijayakumar
Apr 16, 1998·Urological Research·G ItalianoF Pagano
May 23, 1998·Journal of the Neurological Sciences·S J Bird, P M Hanno
May 15, 1998·The New England Journal of Medicine·I GoldsteinP A Wicker
May 20, 1998·Urology·J P GanemC C Carson
Jan 13, 1999·International Journal of Impotence Research·A TraishI Goldstein
Feb 10, 1999·JAMA : the Journal of the American Medical Association·M S RendellM D Smith
Mar 31, 1999·Archives of Sexual Behavior·S StoléruD Comar
Apr 16, 1999·Journal of Clinical Laser Medicine & Surgery·D S Choy
Jul 15, 1999·International Journal of Impotence Research·A I El-SakkaT F Lue
Jul 16, 1999·Mayo Clinic Proceedings·A NehraR B Moreland
Jul 17, 1999·Lancet·J S PalmerC F Firlit
Aug 12, 1999·Journal of Neural Transmission·J SianP Riederer
Sep 14, 1999·The American Journal of Medicine·J C Arezzo
Sep 14, 1999·The American Journal of Medicine·S C Apfel
Dec 10, 1999·British Journal of Pharmacology·S CellekS Moncada
Dec 29, 1999·The Journal of the American Osteopathic Association·M J Olek
Dec 30, 1999·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Z AhmedG Terenghi
Jan 27, 2000·The Journal of Urology·J J Mulcahy
Feb 25, 2000·Urology·C D ZippeM M Lakin
Mar 15, 2000·Seminars in Neurology·M P Keller, P F Chance
Apr 6, 2000·The Journal of Spinal Cord Medicine·S ZaslauJ M Vapnek
Apr 7, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·T A ZesiewiczR A Hauser
Jun 15, 2000·The New England Journal of Medicine·T F Lue
Dec 1, 2000·Human Brain Mapping·J RedoutéJ F Pujol
Jun 14, 2001·The Urologic Clinics of North America·A Nehra, R B Moreland


Nov 18, 2005·The Urologic Clinics of North America·Sharron H Francis, Jackie D Corbin
Aug 15, 2003·Current Opinion in Urology·Eric Meuleman
Feb 16, 2018·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Prakash SeppanSathya Bharathy Sathyanathan

Related Concepts

Erectile Dysfunction
Nocturnal Penile Tumescence
Glans Penis

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.