Neuroimaging Appearance of Cerebral Malignant Epithelioid Glioneuronal Tumors in Children.

AJNR. American Journal of Neuroradiology
G OrmanS F Kralik

Abstract

Malignant epithelioid glioneuronal tumor is a rare high-grade, aggressive brain tumor that shows both glial and neuronal differentiation on histopathology but is not included in the current World Health Organization classification. The neuroimaging appearance is variable but may be secondary to the size of the mass and/or location of the tumor. In our series, all epithelioid glioneuronal tumors were encountered in the supratentorial space and included pineal, temporal, and extratemporal lobar cerebral hemisphere locations. When large, the tumors demonstrate cystic degeneration and necrosis, hemorrhage, contrast enhancement, and regions of low apparent diffusion coefficient scalars consistent with patterns seen with other high-grade pediatric brain tumors. The tumors also have a propensity to spread into the meninges at presentation and for distant CSF spread on follow-up imaging.

References

Dec 3, 2004·Neurosurgery·Pascale VarletCatherine Daumas-Duport
Jan 1, 2013·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Luciana PortoElke Hattingen
Nov 10, 2013·AJNR. American Journal of Neuroradiology·S F KralikC Y Ho
Aug 26, 2014·Diagnostic and Interventional Imaging·M Koob, N Girard
Sep 9, 2015·Pediatric Radiology·Tina Y PoussaintThierry A G M Huisman
Oct 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Derek R JohnsonTimothy J Kaufmann

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