Neurologic complications of cardiac tumors

Handbook of Clinical Neurology
D P Roeltgen, Chelsea S Kidwell

Abstract

Cardiac tumors are an uncommon cause for neurologic disease, but if undiagnosed can be associated with devastating neurologic consequences. Primary cardiac tumors, both benign and neoplastic, and metastatic tumors occur. Primary cardiac tumors are more likely to be associated with neurologic embolic complications. Metastatic cardiac tumors are more likely to be associated with valvular distraction, arrhythmia, diminished cardiac output and indirect neurological dysfunction. Primary and metastatic cardiac tumors may result in cerebral metastatic disease. Atrial myxoma, a benign primary cardiac tumor, is the most common cardiac tumor associated with neurologic disease, and most commonly causes cerebral embolization and stroke. The use of thrombolytic therapy for these strokes is controversial. Additionally, delayed manifestations, including aneurysm formation and intracranial hemorrhage, are possible. Aneurysm formation has been described as occurring after removal of the primary tumor. The availability of noninvasive cardiac imaging has significantly helped decrease the neurologic morbidity of cardiac tumors and has led to frequent successful intervention.

Citations

Jan 26, 2017·Heart, Lung & Circulation·Małgorzata ZachuraMarianna Janion
Feb 1, 2019·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Odysseas KargiotisGeorgios Tsivgoulis
Feb 27, 2019·Current Neurology and Neuroscience Reports·Madalena RosárioJosé M Ferro
Dec 11, 2019·The International Journal of Neuroscience·Mingming DongLi Tian
Aug 15, 2018·Neurology. Clinical Practice·Ana Moreno-EstébanezTomás Pérez-Concha

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