Neurologic Involvement in COVID-19: Cause or Coincidence? A Neuroimaging Perspective.

AJNR. American Journal of Neuroradiology
A Pons-EscodaN Calvo

Abstract

The rapid spread of the coronavirus disease 2019 (COVID-19) pandemic has shaken hospitals worldwide. Some authors suggest that neurologic involvement could further complicate the disease. This descriptive study is a cross-sectional review of 103 patients diagnosed with COVID-19 who underwent neuroimaging (of a total of 2249 patients with COVID-19 in our center). Analyzed variables were neurologic symptoms and acute imaging findings. The most frequent symptoms that motivated neuroimaging examinations were mild nonfocal neurologic symptoms, code stroke (refers to patients presenting with signs and symptoms of stroke whose hyperacute assessment and care is prioritized), focal neurologic symptoms, postsedation encephalopathy, and seizures. No cases of encephalitis or direct central nervous system involvement were detected. Thirteen patients presented with acute ischemic events, and 7, with hemorrhagic events; however, most reported multiple vascular risk factors. Despite the large cohort of patients with COVID-19, we found a large number of symptomatic patients with negative neuroimaging findings, and no conclusions can be drawn concerning concrete associations between neuroimaging and COVID-19.

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Citations

Sep 20, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Amir EmamiAli A Asadi-Pooya
Sep 29, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Pablo Naval-BaudinNahum Calvo
Jun 13, 2020·AJNR. American Journal of Neuroradiology·R Jain
Aug 28, 2020·Annals of Clinical and Translational Neurology·Jesper AlmqvistBenjamin V Ineichen
Dec 1, 2020·Frontiers in Neurology·Pedro FraimanMarialuisa Zedde
Dec 21, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Isabel SiowBarnaby Young
Feb 10, 2021·Radiology·Jeffrey P KanneNicola Sverzellati
Nov 4, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Isaac CheruiyotJulius A Ogeng'o
Jan 10, 2021·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Theodoros LadopoulosChristos Krogias
Mar 19, 2021·Physical Therapy·Kirby P MayerAshley A Montgomery-Yates
Jul 6, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Dimitrios SagrisGeorge Ntaios
Jul 22, 2021·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Aravind GaneshLara J Cooke

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